Clinical trial · Observational
Muscle Oxygen Saturation and Functional Capacity in Breast Cancer Survivors
Analysis of Muscle Oxygen Saturation and Functional Variables During Physical Performance Tests in Breast Cancer Survivors
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This cross-sectional observational study aims to assess muscle oxygen saturation (SmO2) in the intercostal, quadriceps, and triceps surae muscles using near-infrared spectroscopy (NIRS) during functional exercise tests in breast cancer survivors. Participants will be grouped based on their previous cancer treatment: hormonal therapy only or hormonal therapy combined with chemotherapy. Functional performance will be evaluated through the 6-Minute Walk Test, 30-Second Sit-to-Stand Test, and a submaximal treadmill test. The study will analyze differences in muscle oxygenation and performance between groups and explore associations with other functional and clinical parameters.
Conditions
Conditions (7)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Breast Cancer Survivorship | — | UNRESOLVED | — |
| Exercise | — | UNRESOLVED | — |
| Functional Capacity | — | UNRESOLVED | — |
| Hormonal Therapy | — | UNRESOLVED | — |
| Muscle Oxygenation | — | UNRESOLVED | — |
| Near-infrared Spectroscopy | — | UNRESOLVED | — |
| Quality of Life | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Functional Exercise Testing and Muscle Oxygen Saturation Measurement | Diagnostic Test | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- label
- Hormonal Therapy Only
- description
- Participants who received only hormonal therapy following breast cancer treatment.
- interventionNames
- Diagnostic Test: Functional Exercise Testing and Muscle Oxygen Saturation Measurement
- label
- Hormonal Therapy + Chemotherapy
- description
- Participants who received both hormonal therapy and chemotherapy.
- interventionNames
- Diagnostic Test: Functional Exercise Testing and Muscle Oxygen Saturation Measurement
Primary outcomes (1)
- measure
- Muscle oxygen saturation (%)
- timeFrame
- Within a single assessment session (~1 hour)
- description
- Measured via NIRS in intercostal, quadriceps, and triceps surae muscles during three functional tests (6MWT, 30CST, treadmill)
Eligibility
Eligibility (as posted)
- Sex
- Female
- Minimum age
- 30 Years
- Maximum age
- 70 Years
Show eligibility criteria text
Inclusion Criteria: * Women aged 30 to 70 years * Clinical history of breast cancer treatment (at least 6 months prior) * Completed primary cancer treatment * Ability to perform physical tests * Signed informed consent Exclusion Criteria: * Recurrence or metastasis * Severe cardiopulmonary or musculoskeletal disease * Neurological or cognitive limitations * Ongoing oncological treatment
References
Publications (0)
Data not yet available