Phase 1, Open-label, Drug-drug Interaction Study to Assess Effect Between Radiprodil and the Co-administered Drugs.

Inclusion Criteria: - Healthy male and female adults between 18 and 55 years of age, inclusive, at Screening.

* Body mass index (BMI) between 18 and 32 kg/m2 (inclusive) and weighs at least 50 kg at Screening.
* Female participants must be non-lactating and of non-child-bearing potential.
* Male participants if engaging in sexual intercourse with a female partner who could become pregnant must agree to use adequate contraception.
* Participant is of Caucasian origin (note: people of Filipino, Chinese, Japanese, Korean, Vietnamese or Asian-Indian origin are excluded due to higher exposure following rosuvastatin administration).
* Ability to provide signed informed consent and to understand and comply with the requirements of the study including dietary requirements and requirement to stay confined on site for the duration of the study

Exclusion Criteria:

* History of contraindications or hypersensitivity to radiprodil or any components of the formulations or history of hypersensitivity to warfarin, midazolam, digoxin, rosuvastatin, omeprazole, or vitamin K.
* Female participants who are pregnant, breastfeeding, or have a positive pregnancy test at Screening.
* History or presence of significant (in the opinion of the PI) cardiovascular, pulmonary, hepatic, renal, hematological, gastrointestinal, endocrine, immunologic, dermatologic, urologic, neurological, malignancy, psychiatric disease, or brain surgery or injury.
* Any surgical or medical condition that, in the opinion of the PI, could interfere with the absorption, distribution, metabolism, or excretion of the drug.
* History of any CS allergic conditions (including drug allergies, asthma, eczema, or anaphylactic reactions, but excluding untreated, asymptomatic seasonal allergies at time of dosing on Day 1).
* History of illicit drug abuse or alcohol abuse use within 2 years of Screening.
* History of suicide attempts or deliberate self-harm, or a score of 4 or 5 on ideation or any suicidal behavior on the C-SSRS.
* Routine consumption of more than 2 units of alcoholic beverages per day or more than 14 units per week (a unit of alcohol is equivalent to 1 can of beer, 1 glass of wine, or the equivalent of 1 alcoholic drink).
* Routine consumption of an average of more than five (5) 240 mL servings of coffee or other caffeinated beverages per day.
* A positive test result for amphetamines, barbiturates, benzodiazepines, cocaine, methadone, methamphetamines, opiates, methylenedioxymethamphetamine, phencyclidine, tetrahydrocannabinol, cotinine, or alcohol at Screening or Day -1.
* Use of marijuana (including prescribed marijuana) within 30 days of Day -1.
* Use of tobacco-containing products and nicotine or nicotine containing products in the 2 months prior to Day 1.
* Use of any IP and prescription drug within 30 days of Day -1 or within 5 half-lives whichever is longer.
* Use of any over-the-counter (OTC) medication, including herbal products within the 14 days or 5 half-lives prior to dosing, whichever is longer.
* Any vaccine within 7 days of Day -1.
* Acute illness within 14 days of study Day 1.
* Surgery within the past 90 days prior to Day 1.
* Any CS ECG abnormality at Screening.
* Received an IP in any clinical trial within 30 days of Day -1.
* Women of childbearing potential using oral, injected or implanted hormonal contraception.