Clinical trial · Observational
Imaging-Guided Classification for Endophytic Renal Tumors: PN Strategies & Outcomes
A Novel Imaging-Guided Classification System for Completely Endophytic Renal Tumors: Strategies for Optimal Partial Nephrectomy and Clinical Outcome Comparison
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Study Title: Imaging-Guided Classification \& Surgical Outcomes in Endophytic Renal Tumors Study Goal: This observational study investigates whether an imaging-guided classification system improves partial nephrectomy (PN) outcomes for completely endophytic renal cell carcinoma (RCC). Main Question: Does preoperative imaging classification reduce complications (e.g., ischemia time, urinary leakage) in PN for endophytic RCC compared to traditional methods? Methods: Patients undergoing PN for endophytic RCC will be grouped based on preoperative imaging classification. Surgical outcomes (complications, renal function) will be tracked for 5 years and compared to non-classified PN cases. Significance: Aims to optimize PN planning, minimize risks, and improve long-term renal preservation in complex RCC cases
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Renal Tumors | Kidney Neoplasm | ALIAS | 0.90 |
Interventions
Interventions (0)
Data not yet available
Design
Arms and outcomes
Arms (3)
- label
- Type1
- description
- The tumor is entirely confined within the renal parenchyma, positioned transversely between the ventral and dorsal aspects of the kidney and sagittally within the relatively avascular zone between the upper and lower polar lines, without invading renal pelvis structures.
- label
- Type2
- description
- The tumor is located on the ventral aspect of the kidney, adjacent to the anterior wall of the calyx, without involvement of the collecting system . IIb: The tumor is situated on the dorsal aspect of the renal pelvis, closely adjacent to the posterior calyceal wall, without invading the collecting system
- label
- Type3
- description
- The tumor occupies the renal hilum region, involves the renal lip or renal sinus, and is closely associated with renal arteries, veins, and the collecting system.
Primary outcomes (4)
- measure
- Surgical technique
- timeFrame
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: 1. Patients who completed partial resection of completely endogenous renal cancer from January 2018 to November 2024 at the Second Hospital of Tianjin Medical University； 2. Older than 18 years. Exclusion Criteria: 1. Patients without clinicopathologic, functional or prognosis data； 2. Patients with unilateral multiple renal tumors , solitary kidney , or comorbid severe medical conditions；
References
Publications (1)
- DERIVEDWang K, Zhang J, Zhou W, Liu Y, Yao Z, Yao J, Liu Y, Zhang J, Liu K, Li G. A Novel Imaging-Guided Classification System for Completely Endophytic Renal Tumors: Strategies for Optimal Partial Nephrectomy and Clinical Outcome Comparison. Ann Surg Oncol. 2026 Mar;33(3):2791-2801. doi: 10.1245/s10434-025-18756-x. Epub 2025 Nov 22. PMID 41273672