Clinical trial · Observational
Prognostic Impact of Adjuvant Therapy in Primary Hepatic Sarcomatoid Carcinoma
Prognostic Impact of Adjuvant Therapy Following Surgical Resection in Primary Hepatic Sarcomatoid Carcinoma: A Retrospective Cohort Study
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
In recent years, researchers have conducted extensive studies on adjuvant therapy following surgical resection of liver cancer, exploring its potential benefits and seeking effective treatment strategies. Given the rarity and high aggressiveness of primary hepatic sarcomatoid carcinoma, there is a lack of reliable clinical evidence on whether postoperative adjuvant therapy can benefit patients, resulting in the absence of established standard guidelines. Therefore, we conducted a single-center retrospective study to assess the potential benefits of postoperative adjuvant therapy for patients of primary hepatic sarcomatoid carcinoma.
Conditions
Conditions (3)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Adjuvant Therapy | — | UNRESOLVED | — |
| Liver Cancer | Malignant Liver Neoplasm | CURATED_EXACT | 0.92 |
| Sarcomatoid Carcinoma | Sarcomatoid Carcinoma | ONTOLOGY_EXACT | 0.98 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| postoperative adjuvant therapy | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- label
- Primary hepatic sarcomatoid carcinoma patients who received adjuvant therapy
- interventionNames
- Procedure: postoperative adjuvant therapy
- label
- Primary hepatic sarcomatoid carcinoma patients who did not receive adjuvant therapy
Primary outcomes (1)
- measure
- Disease-free survival
- timeFrame
- From December 2018 to May 2023
- description
- Disease-free survival (DFS) was defined as the time from liver resection to disease recurrence or death from any cause.
Secondary outcomes (1)
- measure
- Overall survival
- timeFrame
- From December 2018 to May 2023
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: 1. patients who underwent liver resection 2. patients' postoperative paraffin pathology and immunohistochemistry results were reviewed to identify those diagnosed with PHSC Exclusion Criteria: 1. patients who received other anti-tumor treatments before surgery, such as radiofrequency ablation (RFA), transarterial chemoembolization (TACE), radiation therapy (RT), and systemic therapy; 2. patients diagnosed with other specific types of sarcomas; 3. patients with concurrent other malignancies during the course of PHSC; 4. patients who were lost to follow-up or lacked essential clinical data.
References
Publications (0)
Data not yet available