Clinical trial · Observational
Potential Advantages of Robotic Total Gastrectomy in Advanced Middle-Upper Gastric Cancer: A Multicenter Propensity Score Matching Analysis
Potential Advantages of Robotic Total Gastrectomy in Advanced Middle-Upper Gastric Cancer
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This multicenter retrospective cohort study aimed to evaluate the potential advantages of robotic total gastrectomy (RTG) compared to laparoscopic total gastrectomy (LTG) in patients with advanced middle and upper gastric cancer (AMUGC). A total of 1,099 patients who underwent radical total gastrectomy between 2013 and 2020 were included. After strict inclusion and exclusion criteria, propensity score matching (1:1) was conducted to balance baseline characteristics. The primary endpoint was 3-year disease-free survival (DFS), with secondary outcomes including overall survival, recurrence rates and patterns, and perioperative outcomes. All procedures were performed by experienced surgeons following standardized protocols across eight high-volume centers. Data quality was ensured through a centralized electronic system, unified training, and rigorous verification. This study provides real-world evidence on surgical outcomes and long-term prognosis, contributing to clinical decision-making in the treatment of AMUGC.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Advanced Gastric Cancer | Malignant Gastric Neoplasm | CURATED_BROADER | 0.80 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Robotic Total Gastrectomy and Laparoscopic Total Gastrectomy | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- label
- RTG
- description
- Patients who underwent robotic total gastrectomy
- interventionNames
- Procedure: Robotic Total Gastrectomy and Laparoscopic Total Gastrectomy
- label
- LTG
- description
- Patients who underwent laparoscopic total gastrectomy
- interventionNames
- Procedure: Robotic Total Gastrectomy and Laparoscopic Total Gastrectomy
Primary outcomes (1)
- measure
- 3-year Disease-Free Survival (DFS)
- timeFrame
- 3 years after surgery
- description
- Disease-free survival was defined as the time between the date of surgery and date of the last follow-up for recurrence, death, or no recurrence
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 20 Years
- Maximum age
- 85 Years
Show eligibility criteria text
Inclusion Criteria: \- Diagnosed with middle or upper gastric cancer (GC) Pathological stage T2-T4a, N0-N3b, M0 (postoperative) Underwent radical total gastrectomy Exclusion Criteria: \- American Society of Anesthesiologists (ASA) class \> 3 Residual gastric cancer Use of indocyanine green (ICG) during surgery Received neoadjuvant chemotherapy History of concurrent or previous malignancies Combined resection of other organs Lost to follow-up
References
Publications (0)
Data not yet available