Clinical trial · Interventional
Laparoscopic Versus Robot-assisted Left-sided Pancreatectomy for Benign and Pre-malignant Lesions (DIPLOMA-3)
Laparoscopic Versus Robot-assisted Left-sided Pancreatectomy for Benign and Pre-malignant Lesions (DIPLOMA-3): an International Multicenter Patient-blinded Randomized Controlled Trial
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The DIPLOMA-3 trial is an international, multicenter, patient-blinded randomized controlled trial comparing laparoscopic and robot-assisted left-sided pancreatectomy. Patients with an indication for elective left-sided pancreatecomy for benign or premalignant lesions in the body or tail of the pancreas and considered eligible will be randomized between laparoscopic and robot-assisted resection.
Conditions
Conditions (10)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Distal Pancreatectomy (DP) | — | UNRESOLVED | — |
| Minimally Invasive Distal Pancreatectomy | — | UNRESOLVED | — |
| Minimally Invasive Surgery | — | UNRESOLVED | — |
| Minimally Invasive Surgical Technique | — | UNRESOLVED | — |
| Pancreatectomy | — | UNRESOLVED | — |
| Pancreatic Adenoma | — | UNRESOLVED | — |
| Pancreatic Cyst | — | UNRESOLVED | — |
| Pancreatic Cystadenoma | — | UNRESOLVED | — |
| Pancreatic Neoplasms | Pancreatic Neoplasm | ONTOLOGY_EXACT | 0.98 |
| Surgery | — | UNRESOLVED | — |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Laparoscopic minimally invasive left-sided pancreatecomy | Procedure | — | UNRESOLVED |
| Robot-assisted minimally invasive left-sided pancreatecomy | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- ACTIVE_COMPARATOR
- label
- Laparoscopic minimally invasive left-sided pancreatecomy
- description
- Laparoscopic minimally invasive left-sided pancreatecomy
- interventionNames
- Procedure: Laparoscopic minimally invasive left-sided pancreatecomy
- type
- EXPERIMENTAL
- label
- Robot-assisted minimally invasive left-sided pancreatecomy
- description
- Robot-assisted minimally invasive left-sided pancreatecomy
- interventionNames
- Procedure: Robot-assisted minimally invasive left-sided pancreatecomy
Primary outcomes (1)
- measure
- COMPOS-panc left score
- timeFrame
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Age at least 18 years; * Indication for elective left-sided pancreatectomy, either spleen-preserving or non-preserving (because of proven or suspected left-sided benign or premalignant disease); * Both robot-assisted and laparoscopic left-sided pancreatectomy are technically feasible for resection, according to the local treatment team; * Fit to undergo left-sided pancreatectomy according to the surgeon and anaesthesiologist; * Written informed consent Exclusion Criteria: * Suspected pancreatic ductal adenocarcinoma; * Tumor or cyst larger than 8 cm; * Required resection or ablation of organs other than pancreas and spleen; * Tumor involvement or abutment of major vessels (celiac trunk, mesenteric artery or vena cava); * Pregnancy; * Body mass index \>40 kg/m2; * Participation in another study with interference of study outcomes
References
Publications (0)
Data not yet available