Clinical trial · Observational
Evaluation of Swallowing Muscles Using Ultrasonography and Shear Wave Elastography in Patients Receiving Radiotherapy for Nasopharyngeal Carcinoma Diagnosis
NCT06934837CI-TRIAL-00088696completedClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The aim of this study is to evaluate the mylohyoid, geniohyoid and digastric muscles in patients with radiotherapy-induced dysphagia due to nasopharynx cancer using ultrasonography and shear wave elastography (SWE).
Conditions
Conditions (3)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Evaluation of Swallowing Muscles | — | UNRESOLVED | — |
| Patients Receiving Radiotherapy for Nasopharyngeal Carcinoma Diagnosis | — | UNRESOLVED | — |
| Ultrasonography and Shear Wave Elastography | — | UNRESOLVED | — |
Interventions
Interventions (0)
Data not yet available
No intervention recorded.
Design
Arms and outcomes
Arms (2)
- label
- Nasopharynx canser (disease group)
- description
- 16 Stage I nasopharynx cancer patients receiving radiotherapy
- label
- Control (healthy) group
- description
- 16 healthy volunteers from the otorhinolaryngology outpatient clinic
Primary outcomes (3)
- measure
- Swallowing muscle thickness
- timeFrame
- 12 months after radiotherapy.
- description
- Right and left digastric - mylohyoid muscle thickness, as well as geniohyoid thickness using ultrasonography and Shear Wave Elastography. The thickness values of the mylohyoid, geniohyoid and digastric muscles were measured in mm by experienced radiologist.
- measure
- Swallowing muscle pressure
- timeFrame
- 12 months after radiotherapy.
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 65 Years
Show eligibility criteria text
Inclusion Criteria Patient Group: * Volunteered for the study. * Aged 18-65 years. * Diagnosed with Stage I nasopharynx cancer. * Completed radiotherapy treatment at least 12 months prior to the study. * No additional cancer diagnoses. * No history of chemo-radiotherapy. * No prior head-neck trauma or surgery. * No rheumatologic or neuromuscular disorders. * No pre-existing swallowing disorders. * Control Group (Healthy Volunteers): Control group: * Aged 18-65 years. * No history of head and neck cancer. * No prior neck surgery or trauma. * No radiotherapy to the head and neck region. * No rheumatologic or neuromuscular disorders. * No central haemorrhagic or ischemic disease. * No pre-existing swallowing disorders. Exclusion Criterias: * Younger than 18 years or older than 65 years. * Any history of neck interventions (e.g., for cancer metastasis, cervical spine surgery, trauma). * Presence of systemic conditions potentially causing dysphagia (e.g., neurological, rheumatological, metabolic, or muscular disorders). * Previous radiotherapy for reasons other than Stage I nasopharynx cancer (in the patient group). * Any other cancer diagnosis besides Stage I nasopharynx cancer (in the patient group).
References
Publications (0)
Data not yet available
No reference posted for this study.