Safety, Efficacy, and Survival Outcomes of Neoadjuvant/Induction Immunotherapy in Surgical and Radiotherapeutic Management of Non-Small Cell Lung Cancer

Arms (0)

Primary outcomes (2)

1. measure

   Technical Dissection Difficulty (TDD) Rate

   timeFrame

   During the radical surgery (Day 0 of surgery)

   description

   Defined as the intraoperative presence of fibrosis and/or tight adhesion between lymph nodes and surrounding structures around the hilar and fissure. TDD is considered present if either fibrosis or significant adhesion is noted, potentially increasing surgical complexity. Surgical difficulty is assessed based on operative reports and predefined intraoperative criteria, as documented by the operating surgeon.

2. measure

   Disease-Free Survival (DFS)

   timeFrame

   From the date of radical surgery to the date of disease recurrence, progression, death, or last follow-up, up to 5 years.

   description

   Defined as the time from the date of radical surgery to the first occurrence of disease recurrence, progression, or death from any cause. Patients without an event will be censored at the date of the last follow-up. Disease status is determined through radiological, pathological, or clinical assessment as documented during follow-up.