Clinical trial · Interventional
Corneal Changes in Estrogen-Dependent Breast Cancer After Hormonal Treatment
NCT06924229CI-TRIAL-00088449breast cancercompletedPhase 4ClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Aromatase inhibitors (AI) therapy is the treatment of choice for estrogen receptor-positive breast cancer (BC). While AIs effectively suppress tumor growth, estrogen deprivation may have negative impacts on the eyes. This work evaluated the anterior segment changes in estrogen-dependent BC after hormonal treatment.
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Braest Cancer | — | UNRESOLVED | — |
| Dry Eye | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Hormonal treatment | Drug | Hormone Therapy | ALIAS |
Design
Arms and outcomes
Arms (1)
- type
- ACTIVE_COMPARATOR
- label
- patients with breast cancer recieving hormonal treatment
- description
- evaluation of the effect of hormonal treatment on the cornea
- interventionNames
- Drug: Hormonal treatment
Primary outcomes (1)
- measure
- tear break up time test and shirmer test
- timeFrame
- 6 months
- description
- these tests done before starting treatment and in follow up after recieving treatment to evaluate the lacrimal function and dry eye
Secondary outcomes (1)
- measure
- Corneal thickness and endothelium hexagonality
- timeFrame
- 6 months
Eligibility
Eligibility (as posted)
- Sex
- Male
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Females diagnosed with breast cancer Exclusion Criteria: * uncontrolled diabetes , auto immune diseases
References
Publications (0)
Data not yet available
No reference posted for this study.