Clinical trial · Observational
Development of Polygenic Risk Scores in Colon Cancer Patients Through the Study of Ancestry and Diversity in Genetic Maps of the Brazilian Population - ORIGEM Project
NCT06917794CI-TRIAL-00088295ORIGEMenrolling by invitationClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Development of a polygenic risk score based on somatic and germline genetic information from patients with colorectal cancer
Conditions
Conditions (6)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Cancer Predisposition Syndrome | — | UNRESOLVED | — |
| Colo-rectal Cancer | — | UNRESOLVED | — |
| Germline Mutations | — | UNRESOLVED | — |
| Hereditary Cancer | Hereditary Malignant Neoplasm | ALIAS | 0.90 |
| Polygenic Risk Score | — | UNRESOLVED | — |
| Somatic Mutation | — | UNRESOLVED | — |
Interventions
Interventions (0)
Data not yet available
No intervention recorded.
Design
Arms and outcomes
Arms (0)
[]Primary outcomes (1)
- measure
- Elaboration of Poligenic Risk
- timeFrame
- 36mo
- description
- A germline and somatic genetic mapping in Brazilian patients with colon adenocarcinoma, including ancestry, for the development of a polygenic risk score system applicable to the Brazilian population.
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * \> 18 years; * Histologically confirmed diagnosis of colorectal cancer; * Have available tumor material for somatic sequencing, obtained from biopsy or routine surgery; * Sign the informed consent form (ICF) for the study. Exclusion Criteria: • Pregnants
References
Publications (0)
Data not yet available
No reference posted for this study.