Clinical trial · Interventional
Hemithoracic Arc Radiotherapy Post Pleural Decortication
Hemithoracic Volumetric Modulated Arc Radiotherapy as Part of Lung-Sparing Multimodality Therapy in Patients With Malignant Pleural Mesothelioma Phase II Trial
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Malignant Pleural Mesothelioma is an aggressive and refractory disease , the most aggressive treatment plan offered to these patients include trimodalitiy approach with chemotherapy as the mainstay of treatment . the rationale of post operative Radiotherapy is to sterilize the post operative volume to reduce local failure meanwhile minimizing toxicities in this trial we are going to assess the safety and efficacy of Radiotherapy in Mesothelioma patients poat Pleural decortication
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Malignant Pleural Mesothelioma | Pleural Malignant Mesothelioma | ALIAS | 0.90 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| hemithoracic Volumetric Arc Radiotherapy post Pleural decortication | Radiation | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- type
- EXPERIMENTAL
- label
- single arm receiving postoperative radiotherapy
- description
- single arm receiving post operative Radiotherapy to the hemithorax
- interventionNames
- Radiation: hemithoracic Volumetric Arc Radiotherapy post Pleural decortication
Primary outcomes (2)
- measure
- Acute Radiation Toxicity
- timeFrame
- weekly assessment during radiation course and monthly follow up for the first 6 months
- description
- Questionnaire based Follow up about acute Radiation toxicity according to RTOG including dysnea , cough , chest pain , dysnea on effort from grade 1-5
- measure
- late radiation toxicity
- timeFrame
- Bi-monthly fashion of minimum 6 months post radiation course
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Evidence of metastatic disease. * Underwent Pleural decortication. * Able to provide informed consent. Exclusion Criteria: * Poor pulmonary function tests. * Recurrent or palliative cases. * Inability to attend full course of Radiotherapy or follow up visits.
References
Publications (0)
Data not yet available