Clinical trial · Interventional
Study of Lipid Mediators in Chronic Postoperative Pain - LICP
Study of Lipid Mediators in Chronic Postoperative Pain Following Breast Cancer Surgery
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This interventional prospective study aims firstly to investigate variations in lipid levels in blood samples and their potential relationship with the duration and/or intensity of post-operative pain. Secondly, it aims to investigate the activation of peripheral blood mononuclear cells and neutrophils in patient blood samples. The study will enrol women aged 18 years or older who have been newly diagnosed with primary invasive or non-invasive breast cancer requiring surgical removal of the tumour, with or without axillary surgery. The main objectives of the study are To assess whether there is an association between circulating levels of lipid mediators and chronicity (\> 3 months) of postoperative pain after breast cancer surgery. To assess whether circulating levels of lipid mediators can predict chronicity of postoperative pain in breast cancer surgery. To assess the existence of an association between resected tissue levels of lipid mediators and chronicity of postoperative pain in breast cancer surgery. To assess whether tissue levels of lipid mediators can predict chronicity of postoperative pain in breast cancer surgery.
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Breast Cancer Female | — | UNRESOLVED | — |
| Postoperative Pain | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Blood sample + questionnaire | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- Chronic pain
- interventionNames
- Other: Blood sample + questionnaire
- type
- ACTIVE_COMPARATOR
- label
- No chronic pain
- interventionNames
- Other: Blood sample + questionnaire
Primary outcomes (3)
- measure
- Pain intensity
- timeFrame
- Throughout the study, an average of 2 years
- description
- Pain intensity will be evaluated using a standardized questionnaire completed by participants at each medical consultation.
- measure
Eligibility
Eligibility (as posted)
- Sex
- Female
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Women older than 18 years * Newly diagnosed primary invasive or non-invasive breast cancer, requiring surgical excision of the tumor, with or without axillary surgery * Able to give informed consent Exclusion Criteria: * Men * Women aged less than 18 years * Pregnant women * History of major psychiatric disorders * Previous breast or axillary surgery, recurrent disease or detectable metastatic disease at the time of diagnosis * Unable to give informed consent
References
Publications (0)
Data not yet available