Clinical trial · Interventional
Enhancing the Patient Journey to Clinical Trial Enrolment With Navigation to Optimize Accrual
Enhancing the Patient Journey to Clinical Trial Enrolment With Navigation to Optimize Accrual: A Pilot Study for a Prospective, Pragmatic Multi-centre, Stepped Wedge, Cluster Randomized Controlled Trial
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Less than 5% of patient enter clinical trials, despite the fact that many patients facing cancer are recommended to seek out clinical trials. One challenge of finding a clinical trial, is the lack of clinical trials at the patient's home cancer centre. The Clinical Trials Navigator (CTN) program was established to help patients, their families and heath care providers navigate the clinical trials systems across Canada in order to identify meaningful clinical trials for patients and help them enter those trials. The CTN program was piloted in Windsor, Ontario and increased clinical trials accrual for this population by 8%. This study plans to roll out to twenty centres across Canada, mimicing the process. This implementation of the CTN program will be tested by adding centres in a sequential fashion until all centres are added over the 12 month period. The objectives are improved patient enrollment which will be measured by embedded CTNs in each cancer centre, and reporting to the central site. Pre- and post-implementation structured interviews with administrators, physicians, patients and allied health care professionals will be used to assess uptake of the CTN program in each centre and reveal potential barriers to successful implementation of a nation-wide CTN program. The ability of the current CTN program to upscale to twenty centres will be measured by turn-around times of patient reports and through the structured interviews.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Cancer | Malignant Neoplasm | ALIAS | 0.90 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Educational program | Behavioral | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- ACTIVE_COMPARATOR
- label
- Cohort 1: Patients: Pre and post intervention
- description
- In the two time periods: pre - intervention and post-intervention, patient charts will be reviewed to assess referral to and accrual onto clinical trials outside of their home cancer treatment centre.
- interventionNames
- Behavioral: Educational program
- type
- ACTIVE_COMPARATOR
- label
- Cohort 3: Physicians and Health Care Professionals
- description
- This group will be followed throughout the pre and post intervention period with regular surveys requesting input on number of patients referred to and accrued onto clinical trials outside of the patient's home cancer treatment centre.
- interventionNames
- Behavioral: Educational program
Primary outcomes (2)
Eligibility
Eligibility (as posted)
- Sex
- All
Show eligibility criteria text
Inclusion Criteria: * Limited to Thunder Bay and Winnipeg health care professionals and patients; Exclusion Criteria: * People outside of these two expansion sites
References
Publications (0)
Data not yet available