Clinical trial · Observational
The BEACON Trial: Diagnostic Tools for Breast Lymphedema After Treatment for Breast Cancer
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The goal of this observational study is to learn if participants agree to take part in the study, if the methods we are using for the study are feasible for the participants and the researchers, and to study how well two tools (tissue dielectric constant and ultrasound) measure breast edema after breast conserving surgery for breast cancer. Participants who agree to be in the study will be asked to come in for one appointment of approximately two hours. All data will be collected during this one visit. Participants will be asked to fill out two questionnaires regarding their symptoms, and one questionnaire regarding their surgical scar. The research staff will conduct a clinical examination, measure breast edema using ultrasound and tissue dielectric constant, measure arm volume with the perometer and fluid with the SOZO, and take photographs of both breasts.
Conditions
Conditions (4)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Breast Edema | — | UNRESOLVED | — |
| Breast Lymphedema | — | UNRESOLVED | — |
| Lymphedema | — | UNRESOLVED | — |
| Lymphedema, Breast Cancer | — | UNRESOLVED | — |
Interventions
Interventions (0)
Data not yet available
Design
Arms and outcomes
Arms (2)
- label
- Participants with breast edema: N=15
- description
- This group will contain women who report breast edema and have been diagnosed with breast edema through clinical examination
- label
- Participants without breast edema: N=15
- description
- These participants do not report a history of breast edema and do not have a history of breast edema.
Primary outcomes (2)
- measure
- Tissue Dielectric Constant
- timeFrame
- Baseline
- description
- A TDC interbreast ratio ≥ 1.28 in any quadrant will be used as an indicator of breast lymphedema
- measure
- Breast Ultrasound
- timeFrame
- Baseline
- description
Eligibility
Eligibility (as posted)
- Sex
- Female
- Minimum age
- 18 Years
Show eligibility criteria text
All participants must meet the following inclusion criteria: * Be a female between the ages of 18 and 85 years. * Have undergone breast conserving surgery +/- LN removal (sentinel lymph node biopsy (SLNB) or axillary lymph node dissection (ALND) * Have no residual cancer in the breast after definitive breast surgery * Have been treated with radiation therapy and have completed breast cancer treatment (excluding Herceptin and hormonal treatments) at MGH greater than or equal to 3 months ago. * Be able to read and understand English * Understand the proposed study and be willing and fully able to comply with the study procedures * Be a willing participant and be capable of giving and has given informed written consent for entry into the study EXCLUSION CRITERIA Participants will be excluded if they: * Have bilateral BC * Have metastatic or inflammatory BC * Will be excluded from the SOZO measurement of the study if they have implanted cardiac devices or neurostimulators * Have any medical condition that may result in breast swelling; * Uncontrolled congestive cardiac failure, * Arteriovenous haemodialysis, * Current infection or cellulitis of either breast. * Be pregnant or currently breast feeding. * Have a known over-active thyroid or known benign thyroid tumour
References
Publications (0)
Data not yet available