Clinical trial · Observational
Retrospective Evaluation of Minimally-Invasive Surgical Strategies in Ovarian Neoplasms (REMISSION Study)
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This observational study aims to evaluate the outcomes of patients with early-stage epithelial ovarian cancer who are treated with minimally invasive surgery (such as laparoscopic or robotic surgery). Specifically, the study will look at: 1. Post-Surgery Complications * What is the rate of complications within 30 days after surgery? * How often do patients require readmission to the hospital, re-operation, or conversion to open surgery? 2. Cancer Outcomes * What is the rate of cancer upstaging (when the cancer spreads to a more advanced stage during surgery for example because of an intra-operative ovarian cyst rupture)? * What are the overall survival and disease-free survival rates for patients treated with minimally invasive surgery? Researchers will compare two groups of patients: Group 1: Patients with early-stage ovarian cancer treated with minimally invasive surgery. Group 2: Patients with early-stage ovarian cancer treated with open surgery. The goal is to see if there are any differences in post-surgery complications, recovery, and cancer outcomes between the two groups. Fertility-Sparing Treatment: The study will also compare patients who are undergoing fertility-sparing treatments for early-stage ovarian cancer. Two subgroups will be looked at: * Patients receiving fertility-sparing surgery through a minimally invasive procedure. * Patients receiving fertility-sparing surgery through an open surgery. The same outcomes (complications, survival, etc.) will be assessed and compared between these two groups as well.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Early-stage Epithelial Ovarian Cancer | — | UNRESOLVED | — |
Interventions
Interventions (0)
Data not yet available
Design
Arms and outcomes
Arms (2)
- label
- Patients treated with minimally invasive approach
- label
- Patients treated with open surgery
Primary outcomes (5)
- measure
- To assess the number of patients with 30-day post-operative complication in the two groups (minimally invasive surgery and open surgery)
- timeFrame
- From surgery to post-operative day 30
- measure
- To assess the number of patients with 30-day post-operative hospital readmission in the two groups (minimally invasive surgery and open surgery)
- timeFrame
- From surgery to post-operative day 30
- measure
- To assess the number of patients with 30-day post-operative reoperation in the two groups (minimally invasive surgery and open surgery)
- timeFrame
- From surgery to post-operative day 30
Eligibility
Eligibility (as posted)
- Sex
- Female
Show eligibility criteria text
Inclusion Criteria: 1. Patients with apparent early-stage epithelial ovarian cancer at preoperative evaluation 2. Patients who underwent surgery between January 2014 and December 2023 3. Patients who underwent open or minimally invasive surgical staging (Laparoscopic or Robotic-assisted approach) or restaging procedure 4. Patients with final pathology report of Epithelial Ovarian Cancer Exclusion Criteria: 1. Patients who have not performed a complete surgical staging 2. Patients who underwent neoadjuvant chemotherapy 3. Patients with invasive synchronous tumor 4. Patients with no informed consent 5. Patients with ASA class score of 4 or 5
References
Publications (0)
Data not yet available