Clinical trial · Observational
The Impact of Endoscopic Endonasal Skull Base Surgery on Olfaction
NCT06874426CI-TRIAL-00088812Endo-OlfactrecruitingClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
In this study, the research team will investigate the incidence and etiology of olfactory dysfunction following endoscopic endonasal skull base surgery, by combining clinical assessments with histomolecular analysis.
Conditions
Conditions (6)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Craniopharyngioma | Craniopharyngioma | ONTOLOGY_EXACT | 0.90 |
| Endoscopic Pituitary Surgery | — | UNRESOLVED | — |
| Meningioma | Meningioma | ONTOLOGY_EXACT | 0.90 |
| Olfactory Dysfunction | — | UNRESOLVED | — |
| Pituitary Adenoma | Pituitary Neuroendocrine Tumor | ALIAS | 0.90 |
| Pituitary Disease | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Endoscopic endonasal skull base surgery | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (0)
[]Primary outcomes (3)
- measure
- Incidence of olfactory dysfunction
- timeFrame
- From enrollment to the last evaluation 6 months postoperatively
- measure
- Incidence of trigeminal dysfunction
- timeFrame
- From enrollment to the last evaluation 6 months postoperatively
- measure
- Etiology of olfactory and trigeminal dysfunction following endoscopic endonasal skull base surgery
- timeFrame
- Until the end of study (at 3 years)
Secondary outcomes (1)
- measure
- Risk factors for olfactory dysfunction following endoscopic endonasal skull base surgery
- timeFrame
- From enrollment to the last evaluation 6 months postoperatively
- description
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 70 Years
Show eligibility criteria text
Inclusion Criteria: * Adult patients scheduled for endoscopic endonasal skull base surgery Exclusion Criteria: * Pre-existing anosmia * Patients has a history of previous endoscopic endonasal skull base surgery
References
Publications (0)
Data not yet available
No reference posted for this study.