Clinical trial · Interventional
Chlorhexidine Gluconate Versus Saline for Flushing the Surgical Area During Colorectal Cancer Surgery
A Comparative Study of Chlorhexidine Versus Saline Irrigation of the Surgical Area During Colorectal Cancer Surgery: a Multicenter, Stratified Randomized Controlled Trial.
NCT06869096CI-TRIAL-00106897recruitingN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The aim of this study was to compare the effectiveness of chlorhexidine versus saline in flushing the surgical area during colorectal cancer surgery. The primary outcomes included surgical site infection, postoperative complication rates, et al.
Conditions
Conditions (4)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Chlorhexidine | — | UNRESOLVED | — |
| Colorectal Cancer | Malignant Colorectal Neoplasm | CURATED_BROADER | 0.80 |
| Complications | — | UNRESOLVED | — |
| Surgical Site Infection | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Intraoperative area irrigation | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (8)
- type
- EXPERIMENTAL
- label
- Diabetic rectal cancer patients, chlorhexidine irrigation group
- description
- After colorectal cancer surgery, flush the surgical area with chlorhexidine solution 1 minute before suturing the skin.
- interventionNames
- Procedure: Intraoperative area irrigation
- type
- NO_INTERVENTION
- label
- Diabetic rectal cancer patients, saline irrigation group
- type
- EXPERIMENTAL
- label
- Diabetic colon cancer patients, chlorhexidine irrigation group
- interventionNames
- Procedure: Intraoperative area irrigation
- type
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 85 Years
Show eligibility criteria text
Inclusion Criteria: 1. Patients aged 18-85 years, 2. Patients with surgically resectable colorectal tumors confirmed by CT/MRI before surgery 3. All patients had a performance status score of 0 or 1 in the Eastern Tumor Cooperative group 4. American Society of Anesthesiology grade I-III Exclusion Criteria: 1. The tumor may have distant metastasis 2. History of previous abdominal surgery 3. The patient has a history of other malignant tumors diagnosed in the past 5 years and has received radiotherapy and chemotherapy in the past 4. There are obvious contraindications to surgery (obvious abnormal liver and kidney function, pregnancy) 5. Participated in other clinical trials within the past 6 months
References
Publications (0)
Data not yet available
No reference posted for this study.