Clinical trial · Observational
Evaluating Dyspnea in Autoimmune Myasthenia Gravis "Why am I Short of Breath?"
NCT06866652CI-TRIAL-00110987MyaRESPrecruitingClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Individuals with MG (IwMG) experience shortness of breath that may be activity-related, occur at rest and even happen during sleep. Dyspnea is a complex, multidimensional and multifactorial symptom involving sensory perception, cognition and emotion. Identifying the cause(s) of dyspnea in MG may assist in finding therapeutic strategies, reducing discomfort, improving QoL and potentially limiting respiratory deterioration and incidence of MG crisis.
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Dyspnea | — | UNRESOLVED | — |
| Myasthenia Gravis | — | UNRESOLVED | — |
Interventions
Interventions (0)
Data not yet available
No intervention recorded.
Design
Arms and outcomes
Arms (0)
[]Primary outcomes (1)
- measure
- Dyspnea questionnaires
- timeFrame
- baseline
- description
- Dyspnea-12
Secondary outcomes (5)
- measure
- cardiopulmonary exercise test
- timeFrame
- baseline
- description
- cycle ergometer
- measure
- Polysomnography
- timeFrame
- baseline
- description
- evaluation of sleep disordered breathing
- measure
- Functional measures
- timeFrame
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Age ≥18 * Confirmed diagnosis of autoimmune MG * Shortness of breath in daily life: score 1 or 2 on the respiration item on the MG- activities of daily living score * Signed consent form * Affiliated to or beneficiary of a social security scheme Exclusion Criteria: * Known Pregnancy * Known respiratory disorder (other than MG) * Recent (within past 4 weeks) respiratory infection * Current MG crisis or exacerbation (necessitating increase in MG medication \&/or hospital admission) * No dyspnea - score 0 or 3 on the respiration item on the MG- activities of daily living score * Severe cognitive impairment/guardianship
References
Publications (0)
Data not yet available
No reference posted for this study.