Clinical trial · Observational
Review of the Literature and Serie of Patients Who Underwent Reconstruction After Wide Local Excision of Nail Apparatus for Melanoma
Review of the Literature and Retrospective, Single-centre Study of a Series of Patients Who Underwent Reconstruction After Complete Nail Resection.
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Melanomas of the nail bed are often diagnosed at the locally advanced stage. The standard treatment was amputation of the finger or toe, but it has now been established that enlarged excision of the nail plate is sufficient under certain conditions. Reconstruction of the nail system can be performed by several techniques. Here, the investigators present a series of patients reconstructed by INTEGRA (dermal matrix) and skin graft
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Melanoma | Melanoma | ONTOLOGY_EXACT | 0.98 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Patients who have undergone extensive nail resection with reconstruction | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- label
- Patients who have undergone extensive nail resection with reconstruction
- interventionNames
- Other: Patients who have undergone extensive nail resection with reconstruction
Primary outcomes (1)
- measure
- Functional and cosmetic patient satisfaction
- timeFrame
- 3 months minimum postoperative
- description
- Scores AOFAS (feet)(score ranging from 0, maximum disability, to 90, no disability), Scores QUICK DASH(score ranging from 0, no disability, to 100, maximum disability) and Mayowrist score (hands)(score ranging from 0, maximum disability, to 100, no disability)
Secondary outcomes (2)
- measure
- Post-operative complications
- timeFrame
- 3 months minimum postoperative
- description
- Presence or absence of Postoperative complications (inclusion cyst, nail spicule, need for repeat surgery).
Eligibility
Eligibility (as posted)
- Sex
- All
Show eligibility criteria text
Inclusion Criteria: * Patients who have undergone enlarged resection of the nail apparatus with immediate or delayed reconstruction in the setting of acral melanoma of the fingers or toes. Exclusion Criteria: * Patients who have amputation, opposition of the pateint to the study.
References
Publications (0)
Data not yet available