Clinical trial · Observational
The True Face of the Pyramid; Physical Activity Level and Cardiovascular Risk in Patients With Breast Cancer
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Cardiovascular disease (CVD) is the leading cause of morbidity and mortality worldwide. Many risk factors are thought to be important in the development of CVD; however, some risk factors can be controlled. Regular physical activity (PA) is recommended for the entire population for the primary prevention of CVD. PA and physical health are also believed to reduce other CVD risk factors such as body mass index, blood pressure and stress. Although oncological outcome is the most important factor for breast cancer survivors, CVD has emerged as an important cause of death among them. In particular, CVD mortality is known to increase 7 years after breast cancer diagnosis, and death due to CVD is more common in older patients than death from cancer. Higher levels of physical activity compared to low levels measured prior to breast cancer diagnosis were associated with statistically significantly lower all-cause mortality among women diagnosed with breast cancer. For breast cancer survivors, increasing PA during and after treatment has been reported to be safe and effective in improving cancer survival, alleviating cancer-related symptoms and improving quality of life. However, there is a lack of evidence regarding the effect of PA on cardiovascular outcomes in long-term breast cancer survivors.
Conditions
Conditions (3)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Breast Cancer | Malignant Breast Neoplasm | CURATED_EXACT | 0.92 |
| Cardiovascular Disease | — | UNRESOLVED | — |
| Physical Activity | — | UNRESOLVED | — |
Interventions
Interventions (0)
Data not yet available
Design
Arms and outcomes
Arms (0)
[]Primary outcomes (3)
- measure
- Physical Activity Level
- timeFrame
- One Year
- description
- Physical activity level was assessed using a multisensorial PA monitor. The SenseWear Armband (Armband Model MF-SW, BodyMedia, Pittsburgh, USA) was worn on the back of the left-side upper arm over the triceps for at least 7 consecutive days, except for times requiring contact with water, such as bathing and swimming. The monitor estimates energy expenditure using measurements from tri-axial accelerometers and sensors (galvanic skin response, heat flux, and skin temperature). The measured outputs of the SWA is step count
- measure
- Cardiovascular Disease Risk Scoring
- timeFrame
- One Year
- description
- SCORE2
- measure
- Functional exercise capacity
- timeFrame
- one year
- description
- 6 minutes walk test
Eligibility
Eligibility (as posted)
- Sex
- Female
- Minimum age
- 40 Years
- Maximum age
- 80 Years
Show eligibility criteria text
Inclusion Criteria: 1. To be between the ages of 40-80 years, 2. Volunteering to participate in the research, 3. At least 15 months after breast cancer surgery, 4. 6 months after active breast cancer treatment (ie surgery/chemotherapy) 5. Having no problem in reading and/or understanding the scales and being able to cooperate with the tests. Exclusion Criteria: 1. Presence of active infection, 2. Having a neurological disease or other clinical diagnosis that may affect cognitive status, 3. Having musculoskeletal and neurological disease, symptomatic heart disease, previous lung surgery and malignant disease that may affect exercise performance. 4. Presence of unstable hypertension or diabetes mellitus
References
Publications (0)
Data not yet available