Clinical trial · Observational
Effects of Activity on Diabetes Risk Among Breast Cancer Survivors on Endocrine Therapy (ABIDE)
The Effects of Cardiorespiratory Fitness, Physical Activity and Sedentary Behavior on Insulin Resistance Among Breast Cancer Survivors Being Treated With Anti-estrogen Endocrine Therapies
NCT06830486CI-TRIAL-00102564ABIDEcompletedClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The aim of this study is to learn more about how physical activity and cardiorespiratory fitness are related to diabetes risk among breast cancer patients prescribed an endocrine therapy.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Breast Cancer | Malignant Breast Neoplasm | CURATED_EXACT | 0.92 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| No intervention | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- label
- SERM
- description
- These patients are being treated with a SERM for at least one year prior to enrolling in the study.
- interventionNames
- Other: No intervention
- label
- Aromatase Inhibitor
- description
- These patients are being treated with an aromatase inhibitor for at least one year prior to enrolling in the study.
- interventionNames
- Other: No intervention
Primary outcomes (4)
- measure
- Insulin Resistance
- timeFrame
- Immediately after the consent form is signed
- description
- Insulin resistance will be measured through oral glucose tolerance testing
Eligibility
Eligibility (as posted)
- Sex
- Female
- Minimum age
- 18 Years
- Maximum age
- 80 Years
Show eligibility criteria text
Inclusion Criteria: * Female * diagnosed with breast cancer * age 18-80 years * Completed surgery, chemo- and/or radiation therapy * Prescribed aromatase inhibitor or SERM for at least one year from the time of screening Exclusion Criteria: * Age \< 18 or \> 80 * Type 1 diabetes * Type 2 diabetes * Prescribed anti-hyperglycemic medication, insulin, or sulfonylurea. * Pregnant, breastfeeding or planning to become pregnant in next 2 months * Have absolute contraindications to exercise testing which are: 1. Unstable angina 2. Recent myocardial infarction, cardiac surgery, or vascular surgery (\<3 months) 3. Uncontrolled high blood pressure 4. Heart failure 5. Peripheral artery disease (based on report of symptomatic claudication) 6. Hepatic or renal disease 7. Severe arthritis or mobility impairment that would interfere with exercise testing * Suspected cognitive impairment that would prevent understanding or comprehension of study procedures.
References
Publications (0)
Data not yet available
No reference posted for this study.