Clinical trial · Observational
Transdiagnostic Oncology Program in Primary Care
The Transdiagnostic Oncology Program (TOP): a Combined Lifestyle Intervention to Improve the Quality of Life of Cancer Survivors - a Before-and-after Pilot Study in Primary Care
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The goal of this observational study is to learn about how cancer survivors experience a relatively new 12-month interdisciplinary aftercare program called the Transdiagnostic Oncologic Program (TOP). TOP is an innovative program offered as part of routine family-doctor care among several practices in the province Drenthe, the Netherlands. It is coordinated by the family doctor and caried out by an interdisciplinary team, consisting of the family doctor, a physiotherapist, nutritionist, and optionally a psychologist. The main questions this study aims to answer are: * Is TOP feasible and acceptable? * Does TOP lead to improvements in quality of life in cancer survivors? Patients who were eligible for the program (n=54) were asked to participate in research as well. Everyone who participated in TOP (n=19) agreed to participate in this study as well. Those who declined participation (n=35), were asked to serve as controls, of which 16 agreed to do so.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Cancer Survivor | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Transdiagnostic Oncologic Program | Behavioral | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- label
- Cancer survivors taking part in the program
- description
- Eligble cancer survivors who agreed to take part in TOP and in the study.
- interventionNames
- Behavioral: Transdiagnostic Oncologic Program
- label
- Cancer survivors serving as controls
- description
- Eligble cancer survivors who declined to take part in TOP, but agreed to take part in the study. They serve as a convenience control group.
Primary outcomes (2)
- measure
- Feasibility and satisfaction.
- timeFrame
- From baseline to the end of the program, after 1 year.
- description
- Feasibility of the intervention was assessed through attrition and attendance rates and through several questions on an evaluation form at post-intervention (T2), including adverse effects. Serious adverse events were also inquired by the GP. Satisfaction with the intervention was assessed with the same evaluation form at T2.
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 75 Years
Show eligibility criteria text
Eligibility criteria for the program and for the study were the same, with the exception that participants were willing to sign informed consent to participate in the study. Inclusion criteria: * being between ≥18 and ≤ 75 years old * having been diagnosed with cancer at least 6 months ago and/or have been long-term stable. Exclusion criteria: * having severe physical risks due to cancer treatment and / or comorbidities * currently undergoing intensive chemotherapy or other treatment * having cognitive or psychosomatic complaints that interfere with successful participation * having skin cancer, except for melanomas with metastasis * having a life expectancy of \<1 year
References
Publications (1)
- DERIVEDBooij SH, Pieper A, Wester CD, Bultmann U, Waarsenburg EC, Hoenders HJR. The Transdiagnostic Oncology Program (TOP): a multidomain lifestyle intervention to improve the quality of life of cancer survivors - a before-and-after pilot study in primary care. BMC Cancer. 2025 Nov 10;25(1):1745. doi: 10.1186/s12885-025-15063-2. PMID 41214573