Clinical trial · Interventional
The Safety and Efficacy of Combined Microwave Ablation During Limb-sparing Surgery in High-risk Soft Tissue Sarcoma Patients
NCT06802510CI-TRIAL-00085353completedN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Soft tissue sarcoma (STS) is a rare, aggressive malignancy with a high risk of recurrence when invading surrounding structures, and the optimal treatment strategy for safe surgical margin is still unclear. This study aimed to evaluate the safety and efficacy of combined local inactivation by ablation in STS during limb-sparing surgery in high-risk STS patients.
Conditions
Conditions (3)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Ablation Techniques | — | UNRESOLVED | — |
| Microwave | — | UNRESOLVED | — |
| Sarcoma | Sarcoma | ONTOLOGY_EXACT | 0.98 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Microwave Ablation | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- MWA group
- description
- The MWA group received surgical resection combined with local lesion inactivation by MWA
- interventionNames
- Procedure: Microwave Ablation
- type
- NO_INTERVENTION
- label
- Control group
- description
- The control group received standard surgical resection.
Primary outcomes (3)
- measure
- Overall survival (OS)
- timeFrame
- From date of diagnosis until the date of documented death, assessed up to 5 years (up to 5 year)
- description
- Overall survival was defined as the time from diagnosis to last follow-up or death.
Eligibility
Eligibility (as posted)
- Sex
- All
Show eligibility criteria text
Inclusion Criteria: 1. Pathologically confirmed soft tissue sarcoma (FNCLCC grade G2-G3); 2. MRI/CT confirmed tumor invasion beyond anatomical compartments, joint involvement, or encroachment on surrounding tissues (bones, muscle, etc.); 3. After being fully informed of the risks, the patient strongly refuses amputation or wide resection, which leads to irreversible impaired function. 4. Good physical condition, able to tolerate surgery; Exclusion Criteria: 1. Patients with distant metastasis at the time of initial diagnosis; 2. Patients with missing clinical or follow-up data.
References
Publications (0)
Data not yet available
No reference posted for this study.