Clinical trial · Observational
Methylated Biomarkers Predictive of Endometrial Cancer Risk
NCT06800677CI-TRIAL-00085335BioMECactive not recruitingClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The goal of this observational study is to identify endometrial cancer risk predictive biomarkers and to optimise the methodology for their detection and quantification in non-invasive samples.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Endometrial Cancer | Malignant Endometrial Neoplasm | CURATED_BROADER | 0.80 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Hysterectomy | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- label
- Cases
- description
- Women diagnosed with endometrial cancer of any grade, stage and histological type
- interventionNames
- Procedure: Hysterectomy
- label
- Controls
- description
- Women undergoing a hysterectomy for benign indications
- interventionNames
- Procedure: Hysterectomy
Primary outcomes (1)
- measure
- Sensitivity, specificity, negative and positive predictive value of single gene methylation classifiers in predicting the presence of endometrial cancer in minimally- and invasive samples
- timeFrame
- 1 day
Secondary outcomes (1)
Eligibility
Eligibility (as posted)
- Sex
- Female
- Minimum age
- 45 Years
- Maximum age
- 70 Years
Show eligibility criteria text
Inclusion Criteria: 1. Women aged 45-70 years 2. Attending St Mary's Hospital, Manchester for an elective hysterectomy by any route for either the treatment of endometrial cancer or a benign gynaecological condition 3. Able to consent to participation in the study Exclusion Criteria: 1. Presence of malignancy asides from endometrial cancer 2. Undergoing elective hysterectomy for suspected ovarian cancer
References
Publications (0)
Data not yet available
No reference posted for this study.