Clinical trial · Observational
Exploration of the Relationship Between Mismatch Repair Status of Colorectal Cancer and Lymph Node Metastasis Patterns and Pathological High-risk Factors
NCT06798857CI-TRIAL-00098158completedClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This study analyzed the differences in clinical baseline features and survival outcomes between pMMR and dMMR patients. The aim is to evaluate the impact of MMR status on overall survival and disease-free survival of colorectal patients, and to explore the population exempt from extended resection, so as to provide evidence-based medical evidence for the relationship between MMR status, lymph node metastasis pattern and clinicopathological risk factors in colon cancer patients.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Colon Cancer | Malignant Colon Neoplasm | CURATED_EXACT | 0.92 |
Interventions
Interventions (0)
Data not yet available
No intervention recorded.
Design
Arms and outcomes
Arms (2)
- label
- pMMR group
- description
- Pathological immunohistochemical results suggested pMMR
- label
- dMMR group
- description
- Pathological immunohistochemical results suggested dMMR
Primary outcomes (1)
- measure
- DFS
- timeFrame
- From the date of the initial surgery to death or disease recurrence or metastasis,assessed up to 120 months
- description
- Disease Free Survival
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 20 Years
- Maximum age
- 90 Years
Show eligibility criteria text
Inclusion Criteria: * The preoperative diagnosis was primary colon adenocarcinoma; * Undergoing radical surgical treatment; * Postoperative immunohistochemistry to determine MMR status; * Having complete key clinical and follow-up data. Exclusion Criteria: * Previous history of malignant tumors * Concurrent distant metastasis * Receiving preoperative neoadjuvant therapy.
References
Publications (0)
Data not yet available
No reference posted for this study.