Clinical trial · Observational
Pro- and Anti-inflammatory Cytokines in PCOS
Assessment of the Concentrations of Pro- and Anti-inflammatory Cytokines and Their Association With the Metabolic Profile of Women With PCOS
NCT06793085CI-TRIAL-00105866recruitingClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The study will involve measurements and comparisons of the concentrations of pro-inflammatory cytokines: IL-6, TNF-α, IL-18, as well as anti-inflammatory cytokine IL-4 in women with polycystic ovary syndrome (PCOS) and insulin resistance, women with polycystic ovary syndrome without carbohydrate metabolism disorders, and women without PCOS (control group).
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| PCOS (Polycystic Ovary Syndrome) | — | UNRESOLVED | — |
| Reproductive Age | — | UNRESOLVED | — |
Interventions
Interventions (4)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Measurement of fasting tumor necrosis factor α (TNF-α) concentration | Diagnostic Test | — | UNRESOLVED |
| Measurement of interleukin-18 (il-18) concentration | Diagnostic Test | — | UNRESOLVED |
| Measurement of interleukin-4 (il-4) concentration | Diagnostic Test | — | UNRESOLVED |
| Measurement of interleukin-6 (il-6) concentration in blood serum | Diagnostic Test | — | UNRESOLVED |
Design
Arms and outcomes
Arms (3)
- label
- Polycystic ovary syndrome (PCOS)+ insulin resistance (IR)
- interventionNames
- Diagnostic Test: Measurement of interleukin-6 (il-6) concentration in blood serum
- Diagnostic Test: Measurement of fasting tumor necrosis factor α (TNF-α) concentration
- Diagnostic Test: Measurement of interleukin-18 (il-18) concentration
- Diagnostic Test: Measurement of interleukin-4 (il-4) concentration
- label
- Polycystic ovary syndrome (PCOS)+ no insulin resistance (IR)
- interventionNames
- Diagnostic Test: Measurement of interleukin-6 (il-6) concentration in blood serum
- Diagnostic Test: Measurement of fasting tumor necrosis factor α (TNF-α) concentration
- Diagnostic Test: Measurement of interleukin-18 (il-18) concentration
- Diagnostic Test: Measurement of interleukin-4 (il-4) concentration
- label
- No PCOS
- interventionNames
- Diagnostic Test: Measurement of interleukin-6 (il-6) concentration in blood serum
Eligibility
Eligibility (as posted)
- Sex
- Female
- Minimum age
- 18 Years
- Maximum age
- 45 Years
Show eligibility criteria text
Inclusion Criteria: * women aged 18-45 years Exclusion Criteria: * previous removal of at least one ovary * treated diabetes of any type * diagnosed and treated metabolic diseases * diagnosed and treated autoimmune diseases * diagnosed and treated autoinflammatory diseases
References
Publications (0)
Data not yet available
No reference posted for this study.