Clinical trial · Observational
Evaluation of Post-Induction Hypotension Treatment with PRAM Method
Evaluation of Post-Induction Hypotension Treatment with PRAM Method Data in Gynecologic Oncology Cases
NCT06787404CI-TRIAL-00086800active not recruitingClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The goal of this observational study is to compare post-induction hypotension treatments with PRAM method in Gynecologic Oncological Cases. The goal of this observational study is to compare post-induction hypotension treatments with PRAM method in Gynecologic Oncological Cases.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Hypotension on Induction | — | UNRESOLVED | — |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Ephedrine | Drug | — | UNRESOLVED |
| Noradrenalin | Drug | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- label
- Ephedrine
- description
- When post-induction hypotension occurred patients were treated with 5 milligrams ephedrine in this group. If blood pressure does not reach desired levels, same dosage will be repeated 5 minutes later from administration. Maximum 3 doses will be applied and if hypotension ist persist the treatment will changed to rescue treatment.
- interventionNames
- Drug: Ephedrine
- label
- Noradrenaline
- description
- When post-induction hypotension occurred patients were treated with 5 micrograms noradrenaline in this group. If blood pressure does not reach desired levels, same dosage will be repeated 5 minutes later from administration. Maximum 3 doses will be applied and if hypotension ist persist the treatment will changed to rescue treatment.
- interventionNames
- Drug: Noradrenalin
Primary outcomes (2)
- measure
- "Is there a difference in the need for repeated doses of treatments to reach the target blood pressure in patients who develop post-induction hypotension?"
Eligibility
Eligibility (as posted)
- Sex
- Female
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Above 18 years old * Operated for Gynecologic Oncological reasons * BMI\<35 Exclusion Criteria: * Refusal to participate in the study * Additional spinal or epidural anesthesia * Dementia patients from whom consent could not be obtained * Atrial fibrillation with a rapid ventricular response * Patients with difficult ventilation and/or difficult intubation * Left ventricular ejection fraction (EF) below 30% * Severe aortic valve stenosis * Obesity (BMI \>35) * Chronic beta-blocker use
References
Publications (0)
Data not yet available
No reference posted for this study.