Clinical trial · Observational
The Relationship of Psychological Stress With Therapy Efficacy and Prognosis of Gastric Cancer
Cohort Studies of Associations of Psychological Stress With Therapy Efficacy and Prognosis of Gastric Cancer (G-STRESS)
NCT06786169CI-TRIAL-00084952recruitingClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This is the prospective, observational cohort study (G-Distress) to explore the associations of psychological stress with treatment and prognosis of gastric cancer. The participants including the patients diagnosed with gastric cancer who received surgery, chemotherapy and immune checkpoint inhibitors.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Gastric Cancer, Gastroesophageal Junction Cancer | Malignant Gastric Neoplasm | CURATED_BROADER | 0.80 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| psychological stress status | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (3)
- label
- Cohort 1: advanced gastric cancer patients receiving surgery
- interventionNames
- Other: psychological stress status
- label
- Cohort 2: stage III-IV gastric cancer patients receiving preoperative treatment
- interventionNames
- Other: psychological stress status
- label
- Cohort 3: stage IV gastric cancer patients receiving chemotherapy, immunotherapy or ta
- interventionNames
- Other: psychological stress status
Primary outcomes (3)
- measure
- Cohort 1: Disease-free survival (DFS)
- timeFrame
- 3-year
- description
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 80 Years
Show eligibility criteria text
Cohort 1 Inclusion Criteria: 1. Lower age limit of research subjects 18 years old and upper age limit of 80 years old, ECOG (ECOG score standard) performance status of 0 or 1 2. Be proven to be primary adenocarcinoma of gastric cancer and staged II-III by pathological evidences 3. R0 gastrectomy with D2 lymphadenectomy 4. Receiving adjuvant chemotherapy Exclusion Criteria: 1. History of chemotherapy, radiotherapy, immunotherapy or target therapy 2. Multiple primary tumors 3. Suffering from other serious diseases, including cardiovascular, respiratory, kidney, or liver disease, complicated by poorly controlled hypertension, diabetes, mental disorders or diseases 4. Unavailable for R0 resection and D2 lymph node dissection. 5. Patients with stage IV gastric cancer Cohort 2 Inclusion Criteria: 1. Lower age limit of research subjects 18 years old and upper age limit of 80 years old, ECOG (ECOG score standard) performance status of 0 or 1 2. Be proven to be primary adenocarcinoma of gastric cancer and staged III-IV by pathological evidences 3. Receiving gastrectomy 4. Receiving preoperative chemotherapy Exclusion Criteria: 1. Unavailable for chemotherapy, radiotherapy, immunotherapy or target therapy 2. Multiple primary tumors 3. Suffering from other serious diseases, including cardiovascular, respiratory, kidney, or liver disease, complicated by poorly controlled hypertension, diabetes, mental disorders or diseases 4. Unavailable for gastrectomy Cohort 2 Inclusion Criteria: 1. Lower age limit of research subjects 18 years old and upper age limit of 80 years old, ECOG (ECOG score standard) performance status of 0 or 1 2. Be proven to be primary adenocarcinoma of gastric cancer and staged IV by pathological evidences 3. Unavailable for gastrectomy 4. Presence of at least one measurable lesion according to the Response Evaluation Criteria in Solid Tumors version 1.1 Exclusion Criteria: 1. Unavailable for chemotherapy, radiotherapy, immunotherapy or target therapy 2. Multiple primary tumors 3. Suffering from other serious diseases, including cardiovascular, respiratory, kidney, or liver disease, complicated by poorly controlled hypertension, diabetes, mental disorders or diseases
References
Publications (0)
Data not yet available
No reference posted for this study.