Clinical trial · Interventional
Improvement of Depression in Terminal Cancer Patients
Improvement of Depression in Terminal Cancer Patients (IDTCP)
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This study investigates the potential of the water extract of Gastrodia elata Blume (WGE) to alleviate depressive symptoms in terminal cancer patients. In Taiwan, cancer accounts for 25-30% of annual deaths, with terminal patients often experiencing physical pain and psychological distress, including depression. Addressing both physical and psychological challenges is vital in palliative care. Gastrodia elata Blume is a traditional dietary medicine known for its antidepressant, anti-inflammatory, antioxidant, neurotransmitter-regulating, and neuroprotective properties. This trial will recruit 60 hospice patients, randomly divided into two groups: a control group and a WGE experimental group. Assessments will include: 1. General examinations (e.g., height, weight, blood pressure). 2. Non-invasive autonomic nervous system analyses. 3. Patient-reported measures: Quality of Life Scale (EORTC QLQ-C30), Pain Score, and Hospital Anxiety and Depression Scale (HADS). The study hypothesizes that WGE can: 1. Alleviate depressive symptoms. 2. Enhance autonomic nervous system function. 3. Improve the quality of life for terminal cancer patients. This research aims to demonstrate the therapeutic potential of WGE, improving psychological and physiological outcomes for hospice patients.
Conditions
Conditions (3)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Cancer Patients and Depression and Suicide | — | UNRESOLVED | — |
| Depression | — | UNRESOLVED | — |
| Life Quality | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Gastrodia elata Blume water extract | Dietary Supplement | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- Gastrodia elata Blume water extract
- description
- Subjects will receive Gastrodia elata Blume water extract
- interventionNames
- Dietary Supplement: Gastrodia elata Blume water extract
- type
- PLACEBO_COMPARATOR
- label
- Gastrodia elata Blume water extract-like
- description
- Subjects will receive a placebo resembling Gastrodia elata Blume water extract
- interventionNames
- Dietary Supplement: Gastrodia elata Blume water extract
Primary outcomes (4)
- measure
- Reduction in Depressive Symptoms
- timeFrame
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 20 Years
Show eligibility criteria text
Inclusion Criteria: * Age \> 20 years * Diagnosis of terminal cancer, with an expected life expectancy of less than 6 months- * Patients with sufficient cognitive status to respond to the research staff's evaluation questions Exclusion Criteria: * Patients or their families who refuse to participate * Patients who withdraw from the study * Patients who have participated in other research studies within one month before or during the trial * Patients with suicidal tendencies
References
Publications (0)
Data not yet available