Clinical trial · Observational
Exploring Men s Prostate Cancer Genetic Risk Perceptions
Exploring Men s Prostate Cancer Genetic Risk Perceptions and Willingness to Give a Biospecimen for Genetic Risk Testing
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The exploring men's prostate cancer genetic risk perceptions and willingness to give a biospecimen for genetic risk testing study aims to assess prostate cancer genetic risk and susceptibility beliefs among unaffected men of diverse races/ethnicities who are considering undergoing prostate cancer screening and their willingness of men to provide a biospecimen (saliva sample) and test the samples for prostate cancer aggressiveness and determine risk category based on SNP genetic profile.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Prostate Cancer | Malignant Prostate Neoplasm | CURATED_EXACT | 0.92 |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Questionnaire | Other | — | UNRESOLVED |
| Saliva Sample | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- label
- Prostate Cancer Risk Group
- description
- Participants will be asked to provide saliva samples and complete a questionnaire about their Prostate Cancer Genetic Risk beliefs.
- interventionNames
- Other: Questionnaire
- Other: Saliva Sample
Primary outcomes (1)
- measure
- Prostate Cancer Genetic Risk and Susceptibility Beliefs
- timeFrame
- Up to 6 Months
- description
- Prostate Cancer Genetic Risk and Susceptibility beliefs will be summarized based on single items on the Prostate Cancer Risk Perception Questionnaire.
Secondary outcomes (1)
- measure
- Polygenic Risk Score (PRS) of Saliva Samples
- timeFrame
- Up to 6 Months
Eligibility
Eligibility (as posted)
- Sex
- Male
- Minimum age
- 40 Years
Show eligibility criteria text
Inclusion Criteria: * Racially/ethnically diverse men with emphasis on Men of African Ancestry. * Age 40 and older . * No personal prostate cancer history/diagnosis. * With or without family history of prostate cancer. Exclusion Criteria: * Previous personal Prostate Cancer history/diagnosis * Under 40 years of age
References
Publications (1)
- DERIVEDBoxtha C, El-Kolalli S, Denis J, O'Neil A, Vadaparampil ST, Abdulla R, Park H, Park JY, Gwede CK. Feasibility of Recruitment, Perceived Genetic Risk and Susceptibility Beliefs, and Saliva Sample Collection in a Community-Based Prostate Cancer Genetic Risk Pilot Study. Am J Mens Health. 2026 Jan-Feb;20(1):15579883251410526. doi: 10.1177/15579883251410526. Epub 2026 Jan 8. PMID 41506624