Clinical trial · Interventional
"Effect of Low Level Laser Therapy on Neuropathic Pain After Neck Dissection Surgery''
NCT06762574CI-TRIAL-00084410not yet recruitingN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The purpose of the study was to evaluate the effect of Low Level Laser Therapy on neuropathic pain after neck dissection surgery. It was hypothesized that: Low Level Laser Therapy is effective on improving Neuropathic pain post neck dissection surgery .
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Neck Disease, Head and Neck Cancer | — | UNRESOLVED | — |
| Neuropathic Pain | — | UNRESOLVED | — |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Low Level Laser Therapy | Other | — | UNRESOLVED |
| Placebo Low Level Laser Therapy | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- ACTIVE_COMPARATOR
- label
- Study group receive low level laser Therapy and traditional medical treatment
- interventionNames
- Other: Low Level Laser Therapy
- type
- PLACEBO_COMPARATOR
- label
- Control group receive placebo Low Level Laser Therapy and traditional medical treatment
- interventionNames
- Other: Placebo Low Level Laser Therapy
Primary outcomes (1)
- measure
- Neck Neuropathic pain
- timeFrame
- 6 weeks
- description
- \* Douleur Neuropathique 4 questionnaire : It is a screening questionnaire to identify neuropathic pain in clinical practice and research, it showed significant accuracy of 83% sensitivity and 90% specificity.It is made up of seven items related to symptoms and three items related to physical evaluation . Each item is scored 1 if the answer is positive and zero if negative, leading to a minimum score of zero and maximum of 10. Cut-off point is four, being that scores equal to or above 4 suggest neuropathic pain .
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 30 Years
- Maximum age
- 60 Years
Show eligibility criteria text
Inclusion Criteria: * Fiftyـtwo patients of both genders with age ranged between 30 to 60 years will participate in this study. * All patients had neuropathic pain following Unilateral radical neck dissection surgery. * All patients had history of neuropathic pain involving superficial cervical plexus after unilateral radical neck dissection surgery. * All patients had moderate or severe pain of tingling,numbness and electric nature following neck dissection surgery. NP confined to the C2-C4 distributions, involves one or more branches of the SCP;especially in the skin overlying lateral neck . * Informed consent was obtained from every patient enrolled in the trial. * Moderate to severe pain (VAS score \>4). Exclusion Criteria: * A wound in the affected area. * A cervical disk lesion. * Cervical spine fracture or spondylolisthesis. * Rheumatoid arthritis. * Epilepsy or any psychological
References
Publications (2)
- BACKGROUNDde Pedro M, Lopez-Pintor RM, de la Hoz-Aizpurua JL, Casanas E, Hernandez G. Efficacy of Low-Level Laser Therapy for the Therapeutic Management of Neuropathic Orofacial Pain: A Systematic Review. J Oral Facial Pain Headache. 2020 Winter;34(1):13-30. doi: 10.11607/ofph.2310. Epub 2019 Jul 24. PMID 31339967
- RESULTde Andrade AL, Bossini PS, Parizotto NA. Use of low level laser therapy to control neuropathic pain: A systematic review. J Photochem Photobiol B. 2016 Nov;164:36-42. doi: 10.1016/j.jphotobiol.2016.08.025. Epub 2016 Aug 31. PMID 27639607