Clinical trial · Interventional
Holistic Intervention for Cancer Survivors
A Holistic Intervention Approach to Maximize Quality of Life for Cancer Survivors
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
There are many components to defining a cancer survivor's true quality of life. Quality of life (QOL) can be conceptualized as the maximum realization of an individual's potential outcomes of the physical, mental and spiritual aspects defining a human being. These levels of optimization are often limited within certain bounds by a survivor's medical history such as the cancer experience; functional capacities; dietary choices, connectedness and cognitive processing, e.g. perceptions about life situations such as stressors. Often, in intervention studies and within traditional Western medicine practice, focus on optimizing outcomes for cancer survivors is often "siloed", overly focusing on only one aspect of QOL and not accounting for improving other equally important aspects of QOL. A holistic approach, tailored to the unique aspects for that particular survivor, is needed to maximize the individuals overall QOL. Precision scientific data needs to be collected, as well as the cancer survivor's self-report perceptions (qualitative) to truly understand the individual's level of QOL. Thus, both quantitative and qualitative approaches are needed within a holistic approach. Many interventions' impact wanes when complete. Often those individuals that participated revert to previous maladaptive health behaviors. This can occur partly from a lack of a sense of ownership. Therefore, a holistic, structured approach is urgently needed, presented in a manner to enhance individual efficacy that enhances ownership. Strategies should also engage the expanded cancer survivor community thereby improving the health of the general cancer population, helping reduce existing cancer-related health disparities, and eliminating unnecessary costs on an already seriously strained public health system. Here the investigators propose a 16-week pilot project to prove the feasibility and initial efficacy of such a holistic approach to optimize outcomes for the physical, mental and spiritual aspects of QOL as measured with standard instrumentation and qualitative self-report for 30 adult cancer survivors in the San Antonio, Texas area. The investigators will conduct pre, post and a six-month follow-up assessment for QOL.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Cancer | Malignant Neoplasm | ALIAS | 0.90 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Holistic Intervention | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- type
- EXPERIMENTAL
- label
- Holistic Intervention
- description
- The holistic intervention comprises of Aerobic Exercise Prescription, Yoga and Meditation Exercise, Diet Intervention, and Psychosocial Support
- interventionNames
- Other: Holistic Intervention
Primary outcomes (25)
- measure
- Co-Morbidity Index
- timeFrame
- Weeks "0" and "16"
- description
- Number of comorbidities
- measure
- Motivational Style Profile
- timeFrame
- Weeks "0" and "16"
- description
- The Apter Motivational Style Profile (AMSP) measures the dominance of all five pairs of metamotivational states identified in the theory: Telic vs. Paratelic, Autic vs. Alloic, Mastery vs. Sympathy, Negativism vs. Hedonism, and Locus of Control (Internal vs. External). The results of the AMSP questionnaire provide scores for different motivational dimensions, each representing a continuum between two opposing states. These scores indicate where an individual tends to fall on each continuum, reflecting their predominant motivational style. Each dimension has a pair of opposite states, and the scores on the AMSP indicate an individual's tendency toward one pole or the other of each pair. The higher the score on one pole, the more the person is inclined toward that style. Conversely, lower scores on the opposite pole indicate less preference for that state.
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Have been given a diagnosis of any cancer in their lifetime; (active treatment or post treatment; but must be post diagnosis). (Even though the participant may be currently under treatment and limited in functionality, they will be included in the study as this pilot intervention is specifically intended to include any level of functionality, using a an individually designed program for optimizing outcome.) * Have access or use of a mobile phone or computer to complete surveys and respond to text messages. * Be able to speak understand English or Spanish. * Oriented to time and place. Exclusion Criteria: * Currently enrolled in a competing protocol. * Participants will be excluded it they present with any absolute contraindication to exercise testing as detailed by the American College of Sports Medicine Guidelines on Exercise Testing and Exercise Prescription 52. Specifically: * Known significant change in the resting ECG suggesting significant ischemia. * Recent myocardial infarction (within 2 days). * Unstable angina. * Uncontrolled cardiac arrhythmias causing symptoms or hemodynamic compromise. * Severe symptomatic aortic stenosis. * Uncontrolled symptomatic heart failure. * Acute pulmonary embolus or pulmonary infarction. * Acute myocarditis or pericarditis . * Suspected or known dissecting aneurysm.
References
Publications (1)
- DERIVEDMiller MJ, Hughes DC, Darby NT, Calderon T, Patel DI, Serra MC, Ramirez AG, Ortiz A, Almeida GJ. Balance Changes in Adult Cancer Survivors Participating in a 16-Week Therapeutic Yoga Program. Integr Cancer Ther. 2025 Jan-Dec;24:15347354241313048. doi: 10.1177/15347354241313048. PMID 39811878