Clinical trial · Observational
Dysphagia in Head and Neck Cancer With Radiation
The Impact of Swallowing and Nutrition in Head and Neck Cancer Patients Undergoing Chemo or Chemo-radiotherapy.
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This study focuses on swallowing dysfunction, a common issue affecting 60-75% of head and neck cancer patients due to tumor damage, treatment complications, and chemoradiotherapy side effects, which can lead to malnutrition and reduced quality of life. With limited research on the effects of radiation doses on swallowing muscles and nutrition, this study aims to evaluate these impacts in non-surgical patients undergoing radiotherapy, conducting assessments before treatment, three months after, and within one year post-treatment.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Swallowing Function | — | UNRESOLVED | — |
Interventions
Interventions (0)
Data not yet available
Design
Arms and outcomes
Arms (1)
- label
- head and neck cancer patients
- description
- patients with head and neck cancer undergoing radiation therapy
Primary outcomes (1)
- measure
- hypopharyngeal mean peak pressure
- timeFrame
- one year
- description
- hypopharyngeal contraction
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 80 Years
Show eligibility criteria text
Inclusion Criteria: * Patients scheduled to undergo radiotherapy or concurrent chemoradiotherapy ; * Aged between 18 and 80 years; * Able to perform self-care independently (ECOG ≤ 2); * All patients provide written informed consent. Exclusion Criteria: * Patients scheduled to undergo surgical treatment; * Patients with neuromuscular diseases, such as stroke or Parkinson's disease; * Patients with other diseases or complications, including heart disease classified as NYHA functional class ≥ 2 with thrombotic conditions, or lung disease classified as Hugh-Jones grade ≥ 4; * Patients with psychological disorders that may affect their ability to provide informed consent or comply with the study protocol; * Patients who do not consent to undergo high-resolution impedance manometry.
References
Publications (0)
Data not yet available