Clinical trial · Interventional
Multilevel Action Toward Colorectal Cancer and Hepatitis C Education and Screening
Multilevel Action Toward Colorectal Cancer and Hepatitis C Education and Screening (MATCHES)
NCT06745895CI-TRIAL-00083960MATCHESrecruitingN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 17, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260917-000001
Summary
Brief summary (as posted)
This innovative Multilevel Action Toward Colorectal Cancer (CRC) and Hepatitis C Virus (HCV) Education and Screening (MATCHES) intervention aims to promote concurrent HCV and CRC screening among FQHC patients ages 45-75.
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Colorectal Cancer Screening | — | UNRESOLVED | — |
| Hepatitis C Virus | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| MATCHES | Behavioral | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- type
- EXPERIMENTAL
- label
- Multilevel Action Toward Colorectal Cancer and Hepatitis C Education and Screening (MATCHES)
- description
- The MATCHES intervention includes three patient-level intervention strategies that will be rolled out in two waves. Patient-level strategies are: 1) a combined education booklet with information about CRC/CRC screening and HCV infections/liver cancer/HCV screening in English or Spanish, 2) access to free stool-based CRC screening, and 3) access to free HCV antibody testing.
- interventionNames
- Behavioral: MATCHES
Primary outcomes (1)
- measure
- Screening Uptake for Hepatitis C Virus (HCV) and Colorectal Cancer (CRC)
- timeFrame
- Up to 12 Months
- description
- Screening Uptake will be measured by the number of participants who complete both CRC and HCV screening documented via Electronic Health Record (EHR) at 12 months post-intervention.
Secondary outcomes (5)
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 45 Years
- Maximum age
- 75 Years
Show eligibility criteria text
Inclusion Criteria: * Participants must be receiving care at one of the participating FQHC clinics. * Participants must be 45-75 years of age. * Participants must not be up to date with Colorectal Cancer (CRC) screening recommendations such as no colonoscopy in the past 10 years, occult blood test in the past 12 months. * Participants must never have had Hepatitis C Virus (HCV) antibody screening. * Participants must be able to read, write, and understand English or Spanish. * Participants must have no personal history of CRC or current presumptive CRC symptoms such as unresolved rectal bleeding or abdominal pain/bloating. * Participants must be at average risk for CRC (no hereditary CRC syndromes such as lower gastrointestinal (GI) bleeding, persistent diarrhea, bloating, or lower GI pain, no strong family history of CRC). * Participants must be asymptomatic for HCV. * Participants receiving intervention materials must be able and willing to complete surveys and receive the patient level intervention. * Participants completing qualitative interviews must be willing to complete a remote interview via phone or teleconference software such as ZOOM. * Participants completing qualitative interviews must be willing to be audio recorded. * Participants recruited for qualitative interviews only (did not receive MATCHES intervention materials) must have a clinic visit within prior two months. * All Participants must be able to provide informed consent. Exclusion Criteria: * Participants that do not meet all Inclusion Eligibility requirements will be excluded.
References
Publications (1)
- DERIVEDAbdulla R, Boxtha C, Courtney EP, Anyanwu OA, Sutton SK, Chung-Bridges K, Kassaye HG, Philippe E, Mudon KA, Frias E, Parras D, Avrilien N, Friedman M, Turner K, Coronado GD, Champion VL, Tobin JN, Vadaparampil ST, Gwede CK, Christy SM. Multilevel Action Toward Colorectal Cancer and Hepatitis C Education and Screening (MATCHES): Study protocol for a hybrid 1 stepped-wedge multibehavioral randomized trial. Contemp Clin Trials. 2026 Apr;163:108256. doi: 10.1016/j.cct.2026.108256. Epub 2026 Feb 13. PMID 41692274