Clinical trial · Interventional
Prehabilitation Prior to Surgery for Kidney Tumors
Prehabilitation Prior to Surgery for Kidney Tumors: A Randomized Controlled Research Study (Pre-KiT)
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The goal of this clinical trial is to examine if one month of general health optimization before surgery for kidney tumors can help participants recover more quickly from surgery. The optimization process is called prehabiliation, and will last one month. It consists of 1. A comprehensive health assessment 2. Assisted smoking cessation 3. A home exercise program. The investigators will compare an intervention group receiving one month of prehabilitation with a control group receiving the standard of care. Some of the main questions the investigators want to answer are * Are participants in the intervention group more satisfied with their quality of recovery after surgery? * Do participants in the intervention group maintain more of their physical abilites compared to the control group?
Conditions
Conditions (6)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Elderly (People Aged 65 or More) | — | UNRESOLVED | — |
| Kidney Cancers | Malignant Kidney Neoplasm | CURATED_EXACT | 0.92 |
| Prehabilitation | — | UNRESOLVED | — |
| Renal Cancer | Kidney Neoplasm | PROBABILISTIC | 0.70 |
| Renal Cell Cancer | Renal Cell Carcinoma | CURATED_BROADER | 0.80 |
| Stage I Renal Cell Cancer | Renal Cell Carcinoma | CURATED_BROADER | 0.80 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Prehabilitation | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- NO_INTERVENTION
- label
- Control group
- description
- Participants in the control group are scheduled for surgery in compliance with the Danish cancer patient pathway guarantees (within 14 days).
- type
- EXPERIMENTAL
- label
- Intervention with Pre-KiT prehabilitation
- description
- Participants in the intervention group are scheduled for surgery after four weeks of Pre-KiT prehabilitation. The prehabilitation consists of a geriatric guided assessment with relevant targeted interventions, a home exercise program and assisted smoking cessation.
- interventionNames
- Other: Prehabilitation
Primary outcomes (1)
- measure
- Change in quality of recovery from screening to outpatient follow-up 21 days after surgery
- timeFrame
- From enrollment to outpatient follow-up at 21 days after surgery.
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 65 Years
Show eligibility criteria text
Inclusion Criteria: * 65 years or older * cT1 kidney tumor, scheduled for either partial or radical nephrectomy. * Clinical Frailty Scale 3-6 Exclusion Criteria: * It is determined by an attending physician, or at a multi-disciplinary team-conference, that a 2-4 week postponement of surgery will not be beneficial for the participant. * Participant does not understand Danish og English
References
Publications (1)
- DERIVEDJuul-Haslund M, Lund CM, Dolin TG, Schou-Jensen K, Ostergren PB, Vinther A, Thomsen FF, Fode M. Geriatric prehabilitation prior to surgery for kidney tumors: Study protocol for Pre-KiT - A randomized controlled trial. J Geriatr Oncol. 2026 Mar;17(2):102893. doi: 10.1016/j.jgo.2026.102893. Epub 2026 Jan 26. PMID 41592385