Clinical trial · Observational
Renovated Prediction Model for Difficult Transoral and Submental Endoscopic Thyroidectomy
A Functional-oriented Modification of TOaST Based on Partial Preservation of the Lines Alba Cervical
NCT06738888CI-TRIAL-00121192recruitingClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The investigators have previously proposed a prediction model for difficult transoral and submental thyroidectomy through a retrospective study. In order to better promote transoral and submental endoscopic approach for thyroid surgery and to set up an appropriate training course, the investigators aim to refine the procedure through a prospective study.
Conditions
Conditions (3)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Thyroid Cancer | Malignant Thyroid Gland Neoplasm | CURATED_EXACT | 0.92 |
| Thyroid Diseases | — | UNRESOLVED | — |
| Thyroid Nodule | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Modified TOaST with caudal linea alba preservation | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- label
- Conventional TOaST with bilateral strap muscle suspension
- description
- Participants undergoing conventional transoral and submental thyroidectomy. In this group, the linea alba cervicalis is opened caudally toward the suprasternal notch to establish the operative working space. Bilateral symmetric suspension of the strap muscles is performed to standardize surgical exposure.
- label
- Modified TOaST with caudal linea alba preservation
- description
- Participants undergoing modified transoral and submental thyroidectomy. In this group, the linea alba cervicalis is opened only in its cranial portion, with intentional preservation of a visible caudal linea alba-strap muscle fascial bridge. Bilateral symmetric suspension of the strap muscles is performed to create a centered operative window. If exposure is inadequate, the caudal linea alba opening may be extended and the case will be recorded as technical conversion to conventional TOaST.
- interventionNames
- Procedure: Modified TOaST with caudal linea alba preservation
Primary outcomes (3)
- measure
- Postoperative neck functional recovery at 1 month
- timeFrame
Eligibility
Eligibility (as posted)
- Sex
- All
Show eligibility criteria text
Inclusion Criteria: * Clinical diagnosis of differentiated thyroid cancer with a maximum diameter not exceeding 4 cm * Clinical diagnosis of benign thyroid nodule with a maximum diameter not exceeding 6 cm * Absence of suspicious lateral lymph nodes or distant metastases Exclusion Criteria: * Participants with fusion or fixation of lymph nodes in the neck * Participants with history of neck surgery or radiation * Participants with vocal fold fixation by preoperative fibrolaryngoscope * Participants with preoperative examination suggestive of extrathyroidal invasion * Participants with a significantly restricted neck and/or jaw
References
Publications (0)
Data not yet available
No reference posted for this study.