Clinical trial · Interventional
Study on the Value of Three DWI Scanning Sequences in Staging of Gastric Cancer
Comparative Study on the Value of Three DWI Scan Sequences of 3.0T Magnetic Resonance in Staging of Gastric Cancer
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Accurate staging is critical for effective gastric cancer treatment planning. Conventional DWI (C-DWI) has limitations in image quality due to magnetic field inhomogeneity, which hampers precise T staging. This study aims to compare the image quality and T staging accuracy of C-DWI, TSE-DWI, and ZOOMit-DWI (Z-DWI) sequences in MRI examinations of gastric cancer patients. A prospective study plan to enroll 72 gastric cancer patients undergoing preoperative MRI with C-DWI, TSE-DWI, and Z-DWI sequences using a 3.0 T scanner. Quantitative metrics (ADC, SNR, CNR) and image quality were evaluated. T staging accuracy was assessed by comparing MRI results with postoperative pathological staging using ROC analysis.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Gastric Cancer | Malignant Gastric Neoplasm | CURATED_BROADER | 0.80 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Scanning parameter | Diagnostic Test | — | UNRESOLVED |
Design
Arms and outcomes
Arms (3)
- type
- NO_INTERVENTION
- label
- SS-EPI-DWI T-stage of gastric cancer
- type
- OTHER
- label
- TSE-DWI T-stage of gastric cancer
- interventionNames
- Diagnostic Test: Scanning parameter
- type
- OTHER
- label
- ZOOM-DWI T-stage of gastric cancer
- interventionNames
- Diagnostic Test: Scanning parameter
Primary outcomes (1)
- measure
- T staging of gastric cancer
- timeFrame
- one year
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 80 Years
Show eligibility criteria text
Inclusion Criteria: 1. The patient was diagnosed with gastric cancer by pathological biopsy 2. No biopsy was taken within 1 week before MR Examination to rule out the effect of bleeding on the image 3. No contraindications for MRI examination; And exclude serious heart, liver, kidney, cerebrovascular diseases. Exclusion Criteria: 1. The image quality cannot meet the diagnostic criteria; 2. Patients could not tolerate MRI examination, resulting in incomplete MR-related sequence image data.
References
Publications (0)
Data not yet available