Clinical trial · Observational
Ultrasound-guided Thermal Ablation for Bethesda III/IV Thyroid Nodules
Ultrasound-guided Thermal Ablation for Bethesda III/IV Thyroid Nodules: A Multicenter Study
NCT06733753CI-TRIAL-00086054recruitingClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
To evaluate the long-term outcomes of ultrasound-guided thermal ablation for Bethesda III/IV thyroid nodules
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Thyroid Nodule | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| ultrasound-guided thermal ablation | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- label
- ultrasound-guided thermal ablation
- description
- ultrasound-guided thermal ablation
- interventionNames
- Procedure: ultrasound-guided thermal ablation
Primary outcomes (1)
- measure
- volume reduction rate
- timeFrame
- through study completion, an average of 6 months
- description
- The volume reduction rate (VRR)was calculated by the equations: VRR=(\[initial volume-final volume\] × 100)/initial volume
Secondary outcomes (7)
- measure
- rate of complications
- timeFrame
- 1 week
- description
- complications of ablation
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: 1. confirmation of Bethesda III or IV on fine- needle aspiration and negative on Braf V600E test 2. no clinical or imaging evidences of extrathyroidal extension, lymph node metastasis and distant metastasis on ultrasound, neck and chest CT 3. refusal or ineligibility for surgery 4. follow-up time ≥12 months Exclusion Criteria: 1. follicular neoplasm or malignancy findings on biopsy 2. no suspicious of malignancy in US 3. patients with contra-lateral vocal cord paralysis 4. follow- up time less than 12 months
References
Publications (0)
Data not yet available
No reference posted for this study.