Clinical trial · Observational
Oral Health Related Quality of Life in Head and Neck Cancer Survivors Within the First Year Following Treatment
Oral Health Related Quality of Life in Head and Neck Cancer Survivors Within the First Year Following Treatment: a Cross Sectional Study in Egypt
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Oral Health-Related Quality of Life in Head and Neck Cancer Patients Problem Statement: Head and Neck Cancer (HNC) is a significant global health issue, and its incidence is rising. While treatment options have improved, they often lead to severe oral complications, impacting patients' quality of life. Research Gap: Limited research exists on oral health-related quality of life (OHRQoL) among HNC patients in Egypt, particularly focusing on the impact of oral clinical parameters and treatment-related factors. Research Objective: To assess the OHRQoL of HNC patients who have completed treatment within the past 12 months and to identify factors associated with impaired OHRQoL. Methodology: This study will employ a comprehensive approach to evaluate OHRQoL, considering: Oral Clinical Parameters: Oral hygiene status, oral mucositis, and other oral health indicators. Sociodemographic Factors: Age, gender, education, occupation, and socioeconomic status. Treatment-Related Variables: Type of treatment (surgery, radiation therapy, chemotherapy), treatment duration, and dose intensity. Expected Outcomes: The findings of this study will: Quantify the impact of HNC treatment on OHRQoL. Identify key factors associated with impaired OHRQoL. Highlight the importance of standardized oral care for HNC patients. Provide evidence-based recommendations for improving oral health support and enhancing the overall quality of life for HNC survivors. By addressing the oral health needs of HNC patients, this research aims to improve their quality of life and contribute to better long-term outcomes.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Head and Neck Cancer | Malignant Head and Neck Neoplasm | ALIAS | 0.90 |
Interventions
Interventions (0)
Data not yet available
Design
Arms and outcomes
Arms (1)
- label
- Head and Neck Cancer (HNC) Survivors
- description
- Target Population: Age: 18 years and older Diagnosis: Head and Neck Cancer (HNC) Treatment Status: Within the first year post-treatment completion
Primary outcomes (1)
- measure
- European Organization for Treatment of Cancer Quality of Life Questionnaire for Head and Neck Cancer (EORTC QLQ-H&N-35).
- timeFrame
- Assessed once during the study (day 1 of the study)
- description
- EORTC QLQ-H\&N-35 Minimum Score: 0 Maximum Score: 100 Higher Scores: Indicate worse outcomes and more severe symptoms. Domains Evaluated: Functional Domains: Pain and soreness in the mouth and throat Swallowing difficulties Taste and smell alterations Social eating and enjoyment of meals Social contact Sexuality Symptom Scale: Teeth problems Mouth opening difficulties Dry mouth Sticky saliva Coughing Feeling ill Pain killer use Nutritional supplement or feeding tube use Weight loss Weight gain
Eligibility
Eligibility (as posted)
- Sex
- All
Show eligibility criteria text
Inclusion Criteria: * Age 18 years and above * Diagnosed with HNC * Within the first year post-cancer treatment * Scheduled for a routine follow-up visit at AMTH * Presence of at least one molar and one central incisor in each jaw * Able to provide informed consent Exclusion Criteria: * Inability to provide informed consent * Debilitative conditions or cognitive disabilities * Trismus (mouth opening \< 20 mm)
References
Publications (0)
Data not yet available