Clinical trial · Interventional
Exercise and Nutritional Prehabilitation for Head and Neck Cancer Patients
NCT06722508CI-TRIAL-00100978recruitingN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 12, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260912-000001
Summary
Brief summary (as posted)
This study examines the acceptability, feasibility, and safety in developing a prehabilitation program for head and neck cancer patients. The purpose of this research is to access the safety and acceptability of using a prehabilitation program before head and neck cancer surgery.
Conditions
Conditions (4)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Head and Neck Cancer | Malignant Head and Neck Neoplasm | ALIAS | 0.90 |
| Head Cancer | — | UNRESOLVED | — |
| Neck Cancer | Malignant Neck Neoplasm | ALIAS | 0.90 |
| Sarcopenia | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| exercise and nutritional prehabilitation | Behavioral | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- type
- EXPERIMENTAL
- label
- behavioral intervention
- description
- The study involves a behavioral intervention (exercise and nutritional prehabilitation) designed to assess outcomes related to feasibility, acceptability, and safety in head and neck cancer patients. Outcomes are being measured following the intervention over a defined period (from diagnosis through 1-month post-surgery).
- interventionNames
- Behavioral: exercise and nutritional prehabilitation
Primary outcomes (4)
- measure
- Completion Rate of 2-Week Prehabilitation Program
- timeFrame
- 2 weeks
- description
- Percentage of participants who successfully complete the 2-week prehabilitation program for head and neck cancer patients.
- measure
- Participant Safety During the 2-Week Program
- timeFrame
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: New head and neck cancer diagnosis Age \> 18 Exclusion Criteria: 1. Prior treatment for head and neck cancer (surgery and/or radiation) 2. Acute or unstable cardiac conditions (unstable angina or symptomatic severe aortic stenosis) 3. American Society of Anesthesiologists physical status of 4 and 5 4. Disabling orthopedic or neuromuscular disease 5. Cardiac failure (New York Heart Association functional classes III and IV) 6. Severe chronic obstructive pulmonary disease 7. End-stage liver or kidney disease 8. Inability to swallow and/or feeding tube dependence 9. Any other comorbid medical, physical, and/or mental condition that contraindicates exercise or oral nutrition 10. Adults unable to consent 11. Age 17.99 or younger 12. Prisoners, pregnant women, or other vulnerable population
References
Publications (2)
- BACKGROUNDPowell R, Davies A, Rowlinson-Groves K, French DP, Moore J, Merchant Z. Acceptability of prehabilitation for cancer surgery: a multi-perspective qualitative investigation of patient and 'clinician' experiences. BMC Cancer. 2023 Aug 11;23(1):744. doi: 10.1186/s12885-023-10986-0. PMID 37568097
- BACKGROUNDKnols R, Aaronson NK, Uebelhart D, Fransen J, Aufdemkampe G. Physical exercise in cancer patients during and after medical treatment: a systematic review of randomized and controlled clinical trials. J Clin Oncol. 2005 Jun 1;23(16):3830-42. doi: 10.1200/JCO.2005.02.148. PMID 15923576