Clinical trial · Interventional
Role of Platelet Rich Plasma in Bone Regeneration After Enucleation of Odontogenic Jaw Cysts
NCT06721806CI-TRIAL-00083412not yet recruitingN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
in the present study, the effect of PRP on bone regeneration when applied to the site of removal of cyst of the jaws is evaluated. PRP was delivered to the site combined with gelfoam. Thrombin clot accelerator was not used.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| PRP & Jaw Cysts | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| PRP & bone regeneration | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- ACTIVE_COMPARATOR
- label
- PRP and bone regeneration after enucleation of odontogenic jaw cysts
- description
- effect of PRP on regeneration
- interventionNames
- Procedure: PRP & bone regeneration
- type
- PLACEBO_COMPARATOR
- label
- bone regeneration power without PRP
- description
- bone healing without use of PRP
- interventionNames
- Procedure: PRP & bone regeneration
Primary outcomes (2)
- measure
- bone healing
- timeFrame
- 6 months
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 20 Years
- Maximum age
- 50 Years
Show eligibility criteria text
Inclusion Criteria: 1. Size of the cyst more than 2 cm 2. The lesion could be visualized radiographically 3. Patients within the age range of 20 to 50 years Exclusion Criteria: 1. Patients who were alcoholics \& smokers 2. -Patients with systemic diseases 3. History of bleeding tendencies, blood dyscrasia 4. Low platelet count 5. Patients unable or unwilling to return for follow-up
References
Publications (7)
- BACKGROUNDTiwari A. A Traumatic Ulcer Caused by Accidental Lip Biting Following Topical Anesthesia: A Case Report. Cureus. 2023 Apr 29;15(4):e38316. doi: 10.7759/cureus.38316. eCollection 2023 Apr. PMID 37261171
- BACKGROUNDDohan DM, Choukroun J, Diss A, Dohan SL, Dohan AJ, Mouhyi J, Gogly B. Platelet-rich fibrin (PRF): a second-generation platelet concentrate. Part I: technological concepts and evolution. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2006 Mar;101(3):e37-44. doi: 10.1016/j.tripleo.2005.07.008. Epub 2006 Jan 19. PMID 16504849
- BACKGROUNDDohan DM, Choukroun J, Diss A, Dohan SL, Dohan AJ, Mouhyi J, Gogly B. Platelet-rich fibrin (PRF): a second-generation platelet concentrate. Part II: platelet-related biologic features. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2006 Mar;101(3):e45-50. doi: 10.1016/j.tripleo.2005.07.009. Epub 2006 Jan 10. PMID 16504850
- BACKGROUNDIntini G. The use of platelet-rich plasma in bone reconstruction therapy. Biomaterials. 2009 Oct;30(28):4956-66. doi: 10.1016/j.biomaterials.2009.05.055. Epub 2009 Jul 1. PMID 19573909
- BACKGROUNDRathore A, Tiwari A, Nazim M, Gupta AK, Gande M, Krishnakumar J. Detection of Human PapillomaVirus and its Association with Potentially Malignant Disorders and Oral Squamous Cell Carcinoma: A Retrospective Study. J Pharm Bioallied Sci. 2022 Jul;14(Suppl 1):S820-S824. doi: 10.4103/jpbs.jpbs_9_22. Epub 2022 Jul 13. PMID 36110657
- BACKGROUNDRaghavendra KM, Sara TB, Mariam VJ, Bhat GS. Author's reply: Platelet-rich fibrin as an adjunct to palatal wound healing after harvesting a free gingival graft: A case series. J Indian Soc Periodontol. 2014 Nov-Dec;18(6):684-5. doi: 10.4103/0972-124X.147397. No abstract available. PMID 25624621
- BACKGROUNDKulkarni MR, Thomas BS, Varghese JM, Bhat GS. Platelet-rich fibrin as an adjunct to palatal wound healing after harvesting a free gingival graft: A case series. J Indian Soc Periodontol. 2014 May;18(3):399-402. doi: 10.4103/0972-124X.134591.