Clinical trial · Observational
Cognitive Functioning in People With Myasthenia Graivs: Impact on Daily Life Activities, Work, Disability and Quality of Life
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
MYCOG primarily aims to estimate the prevalence of cognitive difficulties in patients with MG treated at Besta Institute. Secondary aims include: a) assess the degree to which cognitive difficulties are associated to work impairment, limitations in ADL, symptoms of anxiety and depression, fatigue, disability and QoL; b) assess whether patients with different MG types show different degrees of cognitive impairment; c) assess whether patients with different MG antibody profiles show different degrees of cognitive impairment; d) assess whether patients under different MG-specific pharmacological treatments show different degrees of cognitive impairment.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Myasthenia Gravis | — | UNRESOLVED | — |
Interventions
Interventions (0)
Data not yet available
Design
Arms and outcomes
Arms (0)
[]Primary outcomes (1)
- measure
- GEMS
- timeFrame
- 22 months
- description
- Global examination of cognitive functioning
Secondary outcomes (10)
- measure
- CRIq
- timeFrame
- 22 months
- description
- Cognitive reserve index
- measure
- ENB-3
- timeFrame
- 22 months
- description
- Brief Neuropsychological battery
- measure
- MG-DIS
- timeFrame
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 99 Years
Show eligibility criteria text
Inclusion Criteria: * Patients with MG, * followed-up at Besta institute * aged 18-99, * able to understand Italian language; Exclusion Criteria: * psychiatric comorbidies of psychotic nature; * do not accept to participate on a voluntary basis; * patients who should be excluded based on physician's judgement; * patients who live in a nursing home for aged or disabled persons; * respiratory impairment (patients under mechanical ventilation)
References
Publications (0)
Data not yet available