Clinical trial · Observational
Mediastinal Recurrence of Lympho-proliferative Disorders: a Biopsy is Needed
NCT06714045CI-TRIAL-00083228completedClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
We would like to emphasise the need to perform a biopsy in patients with suspected persistence/recurrence of disease; the need to carefully plan the access route to minimise the risk of false negatives; the possibility of performing biopsies through all minimally invasive access routes available to the thoracic surgeon ensuring rapid clinical recovery and timely resumption of medical treatment in the event of recurrence.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Lymphoma | Lymphoma | ONTOLOGY_EXACT | 0.90 |
Interventions
Interventions (0)
Data not yet available
No intervention recorded.
Design
Arms and outcomes
Arms (0)
[]Primary outcomes (1)
- measure
- primary outcomes
- timeFrame
- 30 days after the surgery
- description
- Verify the need for histological confirmation in patients undergoing cytotoxic therapy for lymphoma presenting radiological/scintigraphic signs of suspected persistence or mediastinal recurrence of disease.
Secondary outcomes (1)
- measure
- secondary outcomes
- timeFrame
- 30 days after the surgery
- description
- Evaluate the sensitivity and specificity of the surgical techniques used to perform mediastinal biopsy sampling and assess the incidence of complications and hospitalisation times of each type of surgery: needle biopsy, mediastinoscopy, anterior mediastinotomy, cervico-manubriotomy, VATS and other more unusual surgical accesses, normally used in clinical practice for other pathologies as well, chosen from time to time on the basis of scintigraphic and radiological imaging in suspected lymphoma recurrence/persistence.
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: Radiographic/scintigraphic suspicion of lymphoma persistence/recurrence after cytotoxic treatment Patients undergoing mediastinal biopsy procedure Obtaining informed consent. Exclusion Criteria: incomplete or missing data
References
Publications (0)
Data not yet available
No reference posted for this study.