Clinical trial · Interventional
Oral Mucositis Management in Pediatric Oncology Patients
Oral Mucositis Management Supported by MASCC/ISOO Protocols: A Randomized Controlled Trial in Pediatric Oncology Patients
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This study evaluated the impact of an oral mucositis care protocol on the severity of mucositis. The main questions it aims to answer are: -What is the severity of mucositis in parents and children who receive oral mucositis education? The data were collected using a descriptive information form, the Children's International Mucositis Evaluation Scale (ChIMES), and the WHO Oral Mucositis Grading Scale. Standard care was applied to the control group. For the intervention group, an oral care protocol was prepared, and the patients received training. The oral care intervention was applied for 14 days and monitored by the researcher. The patients were monitored for oral mucositis on Days 0, 3, 7, and 14. Those in the intervention group received a calendar for documenting their oral care practices.
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Childhood Oncology | — | UNRESOLVED | — |
| Mucositis Oral | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Oral Mucosit Care Protocol | Behavioral | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- Intervention Group
- description
- Oral mucositis education was given, oral care was requested for 14 days and monitored on days 0, 3, 7 and 14.
- interventionNames
- Behavioral: Oral Mucosit Care Protocol
- type
- NO_INTERVENTION
- label
- Control Group
- description
- Children in the control group will receive standard care. Mouthwash with sodium bicarbonate (after each feeding), mycostatin (2x1) and tranflex (3x1). Toothbrush and dental floss are not used. At the end of the 14th day, the child and caregiver in the control group will receive Oral Care Protocol Training to Prevent Oral Mucositis.
Primary outcomes (8)
- measure
- CHIMES scores
- timeFrame
- day0
- description
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 6 Weeks
- Maximum age
- 18 Weeks
Show eligibility criteria text
Inclusion criteria: * Being between 6 and 18 years, * Having received at least 1 course of chemotherapy, * Having no visual, auditory, or intellectual problems * Speaking and understanding Turkish * Being willing to participate in the research. Exclusion criteria: -Conditions that prevent verbal communication (neurodevelopmental delay, verbal speech difficulties, hearing or hearing problems; oral mucositis).
References
Publications (1)
- DERIVEDErcelik ZE, Bayram D, Erdogan B, Altay N. Effectiveness of oral mucositis management based on MASCC/ISOO guidelines in pediatric oncology patients: a randomized controlled trial. Support Care Cancer. 2026 Mar 21;34(4):349. doi: 10.1007/s00520-026-10393-8. PMID 41863643