Impact of HPV Vaccination Against Cervical Lesions and Genital Warts in Colombia. an Ecological Assessment

The goal of this observational study is to assess the impact of HPV vaccination on cervical lesions and genital warts in Colombian birth cohorts. The study examines the trends in healthcare services usage related to these conditions, particularly among vaccinated and unvaccinated populations. The main questions it aims to answer are: Have health services usage rates for preneoplastic cervical lesions and genital warts decreased among cohorts of girls eligible for HPV vaccination after the vaccine's introduction? Have there been reductions in health services usage for genital warts among male cohorts of the same birth years as vaccinated girls? Researchers will compare health services usage trends between vaccinated and unvaccinated populations, as well as geographical areas with differing levels of HPV vaccination coverage, to evaluate the impact of the HPV vaccination program. Participants will not be directly involved, as this is a retrospective analysis of existing healthcare records from various national databases, assessing the frequency of healthcare services related to preneoplastic lesions and genital warts, as well as vaccination coverage at national, departmental, and municipal levels.

Sex

Female

Minimum age

9 Years

Maximum age

23 Years

Inclusion Criteria:

* Participants must be born between 1996 and 2003 (for vaccinated cohorts).
* Participants born before 1996 (for unvaccinated cohorts) may be included as control groups.
* Participants must have healthcare service records available for analysis related to genital warts or preneoplastic cervical lesions.
* Participants must have received or not received the HPV vaccine, according to the national immunization program records.
* Data must be available for individuals from regions with documented HPV vaccination coverage rates (departments or municipalities).

Exclusion Criteria:

* Participants without available healthcare service records for genital warts or preneoplastic cervical lesions.
* Participants with incomplete or inaccurate vaccination records.
* Participants not born within the specified birth cohort ranges (i.e., after 2003 or before 1996).
* Individuals from regions without accessible data on HPV vaccination coverage.

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