Clinical trial · Interventional
A Smartphone Application (QuitBot) for the Improvement of Smoking Cessation Among American Indians and Alaska Natives, NAITIVE Trial
Navigation and Artificial Intelligence Technology for Indigenous Virtual Education on Smoking Cessation (NAITIVE)
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This clinical trial develops a chatbot smartphone application (app), QuitBot, and text messaging to help American Indians (AI) and Alaska Natives (AN) to quit smoking commercial tobacco (smoking cessation), and evaluates two remote smoking cessation programs to see how well they work for helping AI/AN people quit smoking commercial tobacco. AI/AN populations have one of the highest rates of commercial cigarette smoking of any racial and ethnic group in the United States (US). They also have a higher rate of developing smoking-related cancer but are less likely to quit smoking. The two programs are designed to provide personalized support in setting a smoking cessation goal, tasks to reach the smoking cessation goal, and motivation to remain smoke-free. This may help to keep participants engaged and support them in their quit efforts, and may improve smoking cessation among AI and AN.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Cigarette Smoking-Related Carcinoma | Cigarette Smoking-Related Carcinoma | ONTOLOGY_EXACT | 0.98 |
Interventions
Interventions (5)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Carbon Monoxide Measurement | Procedure | — | UNRESOLVED |
| Interview | Other | — | UNRESOLVED |
| QuitBot Smoking Cessation Chatbot Program | Device | — | UNRESOLVED |
| QuitBot Smoking Cessation Text Messaging Program | Device | — | UNRESOLVED |
| Survey Administration | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- Arm I (QuitBot chatbot)
- description
- Participants participate in the QuitBot program which involves chatbot messages over 42 days. Therapy description withheld to protect the integrity of the study.
- interventionNames
- Device: QuitBot Smoking Cessation Chatbot Program
- Other: Survey Administration
- Other: Interview
- Procedure: Carbon Monoxide Measurement
- type
- ACTIVE_COMPARATOR
- label
- Arm II (QuitBot texting)
- description
- Participants participate in the QuitBot program which involves text messages over 42 days. Therapy description withheld to protect the integrity of the study.
- interventionNames
- Device: QuitBot Smoking Cessation Text Messaging Program
- Other: Survey Administration
- Procedure: Carbon Monoxide Measurement
Primary outcomes (1)
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Self-identifying as American Indian or Alaska Native, either alone or in combination with other races * Age 18 and older * Smoking combustible cigarettes daily in the past year * Interest in quitting smoking * Interest in learning skills to quit smoking * Willing to be randomly assigned * Have daily access to their own Android or iPhone smartphone * Ability to download a smartphone app * Ability to read English * Not currently (i.e., within past 30 days) using other smoking cessation interventions * No prior participation in our studies * No prior use of SFT * No household or family member participating * US residency for the next twelve months * Willingness to complete follow-up assessments at the 3-, 6-, and 12-month follow-ups * Providing email, phone number(s), and mailing address Exclusion Criteria: * The reverse of the inclusion criteria * Pregnant or breastfeeding * Use of other tobacco products (e.g., ceremonial use of tobacco, e-cigarettes) will be assessed but is not an exclusion criterion, as it would limit the study's generalizability
References
Publications (0)
Data not yet available