Clinical trial · Interventional
An Analysis of Medication Adherence Using Televideo and Telephonic Monitoring and Utilization of an Education Protocol
A Prospective Analysis of Medication Adherence Comparing Televideo and Telephonic Modes of Longitudinal Monitoring and Utilization of a Standardized Educational Protocol
NCT06696521CI-TRIAL-00086991completedN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The objective of this study is to evaluate adherence to oral oncologic medication regimens utilizing a standardized education tool to explain the dosing, side effects and purpose of oral chemotherapy via televideo or telephonic interactions. Researchers aim to evaluate whether the modality of education and monitoring impact adherence.
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Adherence, Medication | — | UNRESOLVED | — |
| Cancer | Malignant Neoplasm | ALIAS | 0.90 |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Intervention A- Telephone | Behavioral | — | UNRESOLVED |
| Intervention B- Televideo | Behavioral | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- type
- OTHER
- label
- Telephonic and telemedicine evaluation
- description
- Patients will be randomized to telephonic or telemedicine evaluation during participation in the study
- interventionNames
- Behavioral: Intervention A- Telephone
- Behavioral: Intervention B- Televideo
Primary outcomes (3)
- measure
- Will modality of outreach impact adherence based on medication possession ratio (MPR) or proportion of days covered (PDC)?
- timeFrame
- Through study completion, approximately 4 months
- description
- The MPR and PDC will be calculated along with pill count and OCAS with each interaction through study completion and then evaluated for the individual patient and as an aggregate for all participants.
- measure
- Will modality of outreach impact adherence based on medication pill counts?
- timeFrame
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 99 Years
Show eligibility criteria text
Inclusion Criteria: 1. Has a diagnosis of cancer 2. Receives cancer care at Abramson Cancer Center at Penn Presbyterian Medical Center 3. Physically and cognitively able to provide informed consent 4. Is 18 years or older 5. Is starting an oral cancer agent 6. Has access to the UPENN televideo platform 7. Lives in Pennsylvania Exclusion Criteria: 1. Does not desire to participate in the study 2. Cannot consent for himself/herself 3. Does not have access to the UPENN televideo platform 4. Does not live in Pennsylvania 5. Chemoradiation patients
References
Publications (12)
- BACKGROUNDVrijens B, De Geest S, Hughes DA, Przemyslaw K, Demonceau J, Ruppar T, Dobbels F, Fargher E, Morrison V, Lewek P, Matyjaszczyk M, Mshelia C, Clyne W, Aronson JK, Urquhart J; ABC Project Team. A new taxonomy for describing and defining adherence to medications. Br J Clin Pharmacol. 2012 May;73(5):691-705. doi: 10.1111/j.1365-2125.2012.04167.x. PMID 22486599
- BACKGROUNDVoils CI, Venne VL, Weidenbacher H, Sperber N, Datta S. Comparison of Telephone and Televideo Modes for Delivery of Genetic Counseling: a Randomized Trial. J Genet Couns. 2018 Apr;27(2):339-348. doi: 10.1007/s10897-017-0189-1. Epub 2017 Dec 15. PMID 29243007
- BACKGROUNDTipton JM. Overview of the challenges related to oral agents for cancer and their impact on adherence. Clin J Oncol Nurs. 2015 Jun;19(3 Suppl):37-40. doi: 10.1188/15.S1.CJON.37-40. PMID 26030391
- BACKGROUNDSpoelstra SL, Rittenberg CN. Assessment and measurement of medication adherence: oral agents for cancer. Clin J Oncol Nurs. 2015 Jun;19(3 Suppl):47-52. doi: 10.1188/15.S1.CJON.47-52. PMID 26030393
- BACKGROUNDSpoelstra SL, Given CW. Assessment and measurement of adherence to oral antineoplastic agents. Semin Oncol Nurs. 2011 May;27(2):116-32. doi: 10.1016/j.soncn.2011.02.004. PMID 21514481
- BACKGROUNDSirintrapun SJ, Lopez AM. Telemedicine in Cancer Care. Am Soc Clin Oncol Educ Book. 2018 May 23;38:540-545. doi: 10.1200/EDBK_200141. PMID 30231354
- BACKGROUNDBurhenn PS, Smudde J. Using tools and technology to promote education and adherence to oral agents for cancer. Clin J Oncol Nurs. 2015 Jun;19(3 Suppl):53-9. doi: 10.1188/15.S1.CJON.53-59. PMID 26030395
- BACKGROUNDSiegel RL, Miller KD, Jemal A. Cancer statistics, 2020. CA Cancer J Clin. 2020 Jan;70(1):7-30. doi: 10.3322/caac.21590. Epub 2020 Jan 8.