Clinical trial · Interventional
Fitness and Nutrition in Glioma
A Pilot Study to Investigate the Effects of Combining a Modified Atkins Diet With a Physical Fitness Regimen in Patients Diagnosed With Malignant Glioma
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This is a pilot study assessing the effects of combining a modified Atkins diet with a physical fitness regimen in patients with malignant glioma. A sample size of 15 participants will be enrolled in a 15-week program consisting of two weekly supervised exercise sessions combined with an individualized home exercise program and a modified Atkins diet.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Malignant Glioma | Malignant Glioma | ONTOLOGY_EXACT | 0.98 |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Fitness Program | Behavioral | — | UNRESOLVED |
| Modified Atkins Diet | Behavioral | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- type
- EXPERIMENTAL
- label
- Patients Diagnosed with Malignant Glioma
- description
- Patients will participate in a 15-week program consisting of two weekly supervised exercise sessions combined with an individualized home exercise program and a modified Atkins diet.
- interventionNames
- Behavioral: Modified Atkins Diet
- Behavioral: Fitness Program
Primary outcomes (2)
- measure
- Change in Short Form (SF)-36 Version 2 Score
- timeFrame
- Baseline, Week 12
- description
- The SF-36
- measure
- Number of Participants who Complete Full 12-Week Program
- timeFrame
- Week 12
Secondary outcomes (9)
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 100 Years
Show eligibility criteria text
Inclusion Criteria: * Tissue confirmed diagnosis of high-grade glioma (World Health Organization grade III or IV) * Karnofsky Performance Status (KPS) ≥ 70% * Willing to follow the study intervention and follow-up * Able to give full informed consent Exclusion Criteria: * Currently undergoing initial concurrent radiation/chemotherapy * Severe medical co-morbidities * Any medical condition which prohibits moderate to vigorous physical activity (60-85% HRmax) * Any medical condition which prohibits a restrictive diet * Neurological deficit preventing participation in moderate to vigorous physical activity * Severe psychiatric illness
References
Publications (0)
Data not yet available