Clinical trial · Interventional
Exercise During Chemotherapy Treatment As Adjuvant Program in Patients with Lymphoma: EDONOLA Study.
Ejercicio Físico Durante El Tratamiento De Quimioterapia Como Programa Adyuvante En Pacientes Con Linfoma: Estudio EDONOLA
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
In people diagnosed with lymphoma receiving immunochemotherapy treatment, a combined exercise intervention, as opposed to the general recommendations, will achieve: 1.Improve cardiorespiratory fitness, strength, psychological well-being and quality of life. //2.Reduce fatigue//3.Reduce frailty There is an association between some biological biomarkers with physical capacity and frailty.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Lymphoma | Lymphoma | ONTOLOGY_EXACT | 0.90 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Exercise | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- NO_INTERVENTION
- label
- Control Group
- description
- The control group will receive the usual care and indications.
- type
- EXPERIMENTAL
- label
- Intervention Group
- description
- The interventional group will add a exercise program.
- interventionNames
- Other: Exercise
Primary outcomes (1)
- measure
- Cardiorespiratory fitness (CRF)
- timeFrame
- 20 weeks
- description
- Measured by peak oxygen uptake (VO2peak) before starting chemotherapy treatment and after 20 weeks of intervention, using the cardiorespiratory exercise test.
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Age: ≥18 years old. * Diagnosis of lymphoma with histological confirmation and requirement of systemic treatment including chemotherapy. * Time available (80 minutes, two days a week for 20 weeks) to carry out physical exercise sessions. * Have a mobile phone to be able to contact the person and download the physical activity level app. * Eastern Cooperative Oncology Group performance status (ECOG) ≤2. * Life expectancy \>12 months. * Availability and desire to participate throughout the study period. Exclusion Criteria: * Have a contraindication to moderate-high intensity exercise. * Other significant medical disorders: including psychiatric illnesses chronic or recurrent; intellectual disability, musculoskeletal problems, cardiac or pulmonary disorders that interfere with physical exercise; other malignant tumors in the last five years, with the exception of therapeutically controlled skin cancer; any other illness that may be seen affected or aggravated by physical exercise. * Have plans to be outside city more than two weeks. * People who are already physically active (that comply with the recommendations of WHO: \> 150 minutes of exercise moderate/weekly, plus training force two days/week). * Treatment based only with immunotherapy. * Central nervous system involvement due to lymphoma. * Have any important history that limit the capacity of the patient to participate in the study.
References
Publications (0)
Data not yet available