Clinical trial · Observational
Comparison Between Whole Body DWI and FDG PET/CT in Patients with Simptomatic Multiple Myeloma
Whole Body DWI Sequences As Compared with Standard FDG PET/CT in Patients with Simptomatic Multiple Myeloma
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The primary objective is to evaluate the concordance of FDG PET/CT and total body DWI MRI sequences performed during staging and at the completion of therapy. Specifically, we will assess the positivity rates, both patient-based and lesion-based (total and by district), of the two methods during staging and at the completion of therapy. An interim analysis will be conducted comparing the two methods, followed by a final prognostic analysis.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Multiple Myeloma | Multiple Myeloma | CURATED_EXACT | 0.92 |
Interventions
Interventions (0)
Data not yet available
Design
Arms and outcomes
Arms (1)
- label
- patients with new diagnosis of symptomatic multiple myeloma
- description
- fdg pet/CT and Whole body MRI with DWI
Primary outcomes (1)
- measure
- positivity rate
- timeFrame
- 33 months
- description
- comparison per patient and per lesion between FDG PET CT and WB DWI
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * • Patients with symptomatic myeloma in the staging phase or with suspected symptomatic myeloma in the diagnostic phase * Patients who have signed the informed consent form Exclusion Criteria: * Patients simultaneously affected by other neoplastic diseases or with a history of other neoplasms in the previous 5 years * Age \< 18 years * Women who are breastfeeding or pregnant * Patients with metal implants or devices that constitute an absolute contraindication for MRI * Patients with severe claustrophobia * Patients with bone pain that prevents prolonged maintenance of the supine position
References
Publications (0)
Data not yet available